Evidence map›Paper›PMID 28985367›Full record

ArticleGenome biology and evolution2017

The Novel Evolution of the Sperm Whale Genome.

Wesley C Warren, Lukas Kuderna, Alana Alexander, Julian Catchen, José G Pérez-Silva, Carlos López-Otín, Víctor Quesada, Patrick Minx, Chad Tomlinson, Michael J Montague and 9 more

Erratum issuedAbstract read
In one paragraph

Article in Genome biology and evolution, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

19 authors.

Wesley C WarrenMcDonnell Genome Institute, Washington University, St Louis.
Lukas KudernaInstitute of Evolutionary Biology (UPF-CSIC), PRBB, Barcelona, Spain.
Alana AlexanderBiodiversity Institute, University of Kansas.
Julian CatchenDepartment of Animal Biology, University of Illinois, Urbana.
José G Pérez-SilvaDepartamento de Bioquímica y Biología Molecular, Facultad de Medicina, Instituto Universitario de Oncología, Universidad de Oviedo, Spain.
Carlos López-OtínDepartamento de Bioquímica y Biología Molecular, Facultad de Medicina, Instituto Universitario de Oncología, Universidad de Oviedo, Spain.
Víctor QuesadaDepartamento de Bioquímica y Biología Molecular, Facultad de Medicina, Instituto Universitario de Oncología, Universidad de Oviedo, Spain.
Patrick MinxMcDonnell Genome Institute, Washington University, St Louis.
Chad TomlinsonMcDonnell Genome Institute, Washington University, St Louis.
Michael J MontagueDepartment of Neuroscience, Perelman School of Medicine, University of Pennsylvania.
Fabiana H G FariasMcDonnell Genome Institute, Washington University, St Louis.
Ronald B WalterDepartment of Chemistry and Biochemistry, Texas State University.
Tomas Marques-BonetInstitute of Evolutionary Biology (UPF-CSIC), PRBB, Barcelona, Spain.
Travis GlennDepartment of Environmental Health Science, University of Georgia, Environmental Health Science Bldg, Athens, Georgia.
Troy J KieranDepartment of Environmental Health Science, University of Georgia, Environmental Health Science Bldg, Athens, Georgia.
Sandra S WiseWise Laboratory of Environmental and Genetic Toxicology, Department of Pharmacology and Toxicology, School of Medicine, University of Louisville.
John Pierce WiseWise Laboratory of Environmental and Genetic Toxicology, Department of Pharmacology and Toxicology, School of Medicine, University of Louisville.
Robert M WaterhouseDepartment of Ecology and Evolution, University of Lausanne, Switzerland.
John Pierce WiseWise Laboratory of Environmental and Genetic Toxicology, Department of Pharmacology and Toxicology, School of Medicine, University of Louisville.

Funding

PARTICULATE CR(VI) TOXICOLOGY IN HUMAN LUNG EPITHELIAL CELLS AND FIBROBLASTS (Admin Supplement/PA-17-055)R01ES016893 · NIEHS · UNIVERSITY OF SOUTHERN MAINE · PI WISE, JOHN PIERCE · 2009 to 2021
$5.1M
Whole genome assembly resources for aquatic models of human diseaseR24OD011198 · OD · WASHINGTON UNIVERSITY · PI WARREN, WESLEY CHARLES · 2012 to 2019
$1.4M
NIEHS NIH HHS R01 ES016893NIH HHS R24 OD011198
6 · The paper itself

Abstract

The sperm whale, made famous by Moby Dick, is one of the most fascinating of all ocean-dwelling species given their unique life history, novel physiological adaptations to hunting squid at extreme ocean depths, and their position as one of the earliest branching toothed whales (Odontoceti). We assembled the sperm whale (Physeter macrocephalus) genome and resequenced individuals from multiple ocean basins to identify new candidate genes for adaptation to an aquatic environment and infer demographic history. Genes crucial for skin integrity appeared to be particularly important in both the sperm whale and other cetaceans. We also find sperm whales experienced a steep population decline during the early Pleistocene epoch. These genomic data add new comparative insight into the evolution of whales.

Indexed as

Evolution, MolecularGenomeAnimalsDNA, MitochondrialPhylogenySperm WhaleDNA, Mitochondrialcetaceansgenomesperm whale

Identifiers

PMID28985367
PMCPMC5726484

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.