ArticleJournal of Alzheimer's disease : JAD2017
Dementia Prevalence in a Rural Region of South Africa: A Cross-Sectional Community Study.
Article in Journal of Alzheimer's disease : JAD, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 2 of them syntheses that pooled it.
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Who cites it
41 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Cognitive Stimulation Therapy for older people with Dementia in Africa: A Scoping Review.Open research Africa · 2023Pooled it
- Dominant and Modifiable Risk Factors for Dementia in Sub-Saharan Africa: A Systematic Review and Meta-Analysis.Frontiers in neurology · 2021Pooled it
- Article
- Cohort profile: a community-based prospective cohort study of Alzheimer's disease and related dementias in the Democratic Republic of Congo.Alzheimer's & dementia. Behavior & socioeconomics of aging · 2026Article
- Deciphering Antidiabetic, Anti-Inflammatory, and Anti-Cholinergic Bioactivities of Withania somnifera (L) Dunal Root Extract: An In Vitro and In Silico Investigation.Chemistry & biodiversity · 2026Article
- Knowledge and attitudes towards Alzheimer's disease and related dementias among Nigerian medical and nursing students: a comparative study.BMC medical education · 2025Article
- An uncommon variant of Alzheimer's disease: Posterior cortical atrophy.The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa · 2025Article
- Giving voice to the voiceless: Understanding the perceived needs of dementia family carers in Soweto, a South African township.Dementia (London, England) · 2024Article
- Tube feeding in advanced dementia: Insights from South African speech-language therapists.The South African journal of communication disorders = Die Suid-Afrikaanse tydskrif vir Kommunikasieafwykings · 2024Article
- Prevalence of Dementia and Cognitive Impairment in East Africa Region: A Scoping Review of Population-Based Studies and Call for Further Research.Journal of Alzheimer's disease : JAD · 2024Article
- Montreal Cognitive Assessment test: Psychometric analysis of a South African workplace sample.African journal of psychological assessment · 2024Article
- Prevalence and risk factors for Alzheimer's disease and related dementias in Ghana: Evidence from a cross-sectional population-based study.Cogent public health · 2024Article
- Screening for dementia and associated factors in older adults from low socioeconomic communities in iLembe, KwaZulu-Natal.Health SA = SA Gesondheid · 2024Article
- Sensitivity of the African neuropsychology battery memory subtests and learning slopes in discriminating APOE 4 and amyloid pathology in adult individuals in the Democratic Republic of Congo.Frontiers in neurology · 2024Article
- Dementia Screening in Rural Kenya: The Prevalence and Impact of Screening Positive for Dementia.Neuroepidemiology · 2024Article
- Prevalence of suspected dementia in a sample of adults living in Kinshasa-Democratic Republic of the Congo.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2023Article
- Comprehensive measurement of the prevalence of dementia in low- and middle-income countries: STRiDE methodology and its application in Indonesia and South Africa.BJPsych open · 2023Article
- Prevalence, factors associated and knowledge of probable dementia among adults 50 years and over attending a faith-based geriatric center in Uganda.Scientific reports · 2023Article
- Proposing novel natural compounds against Alzheimer's disease targeting acetylcholinesterase.PloS one · 2023Article
- Understanding the lived experiences of family caregivers of individuals with dementia in Soweto, a South African Township.Dementia (London, England) · 2022Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDementia is a growing concern for low- and middle-income countries where longevity is increasing and service provision is poor. Global prevalence estimates vary from 2% to 8.5% for those aged 60 years and older. There have been few dementia studies in sub-Saharan Africa, and prevalence data are lacking for South Africa.
objectiveTo conduct a large dementia prevalence study in a low income rural population in South Africa.
methods1,394 Xhosa-speaking community dwellers, aged ≥60 y (mean age±sd 71.3±8.3 y), in three clinic catchment areas, were screened at home. Trained community health workers administered the brief Community Screening Instrument for Dementia (CSID) to participants and informants to assess cognitive and functional capacity. Depressive symptoms were assessed with three questions from the EURO-D.
resultsThe prevalence estimate using published CSID sensitivity/specificity values was 0.8 (95% CI: 0.06-0.09). Using CSID cut-off scores the estimated prevalence was 0.12 (95% CI: 0.10-0.13), with 161 screen-positives. Both methods gave a rate of 0.11 (95% CI: 0.09-0.13) for those over 65 years (n = 1051). 68.6% of participants were female and 69.8% had less than 7 years of education. Dementia risk was associated with older age and symptoms of depression, but not with sex. The association with education was not significant when controlled for by age.
conclusionsDementia prevalence estimates were higher than expected for this low-income rural community. There is a need for increased dementia awareness and feasible support interventions. We also need further studies of regional prevalences, dementia subtypes, and modifiable risk factors in South Africa.
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