Evidence map›Paper›PMID 28984573›Full record

ArticleeLife2017

Sleep homeostasis regulated by 5HT2b receptor in a small subset of neurons in the dorsal fan-shaped body of drosophila.

Yongjun Qian, Yue Cao, Bowen Deng, Guang Yang, Jiayun Li, Rui Xu, Dandan Zhang, Juan Huang, Yi Rao

Open access · goldAbstract read
In one paragraph

Article in eLife, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed
4.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

73 citing papers in PubMed, 125 citations in OpenAlex.

  1. Article
  2. Article
  3. Hormonal control of postmitotic neuronal identity.bioRxiv : the preprint server for biology · 2026
    Article
  4. Inferring the genetic basis of sleep states inbioRxiv : the preprint server for biology · 2026
    Article
  5. Review
  6. Sleep regulation inFrontiers in neuroscience · 2026
    Review
  7. 25 years ofFly · 2025
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Constitutive and Conditional Epitope Tagging of Endogenous G-Protein-Coupled Receptors inThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  18. Article
  19. Article
  20. Article

13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Yongjun QianPeking-Tsinghua Center for Life Sciences, State Key Laboratory of Biomembrane and Membrane Biology, PKU-IDG/McGovern Institute For Brain Research, Beijing Advanced Innovation Center for Genomics, School of Life Sciences, Peking University, Beijing, China.ORCID 0000-0002-2696-6730
Yue CaoPeking-Tsinghua Center for Life Sciences, State Key Laboratory of Biomembrane and Membrane Biology, PKU-IDG/McGovern Institute For Brain Research, Beijing Advanced Innovation Center for Genomics, School of Life Sciences, Peking University, Beijing, China.
Bowen DengPeking-Tsinghua Center for Life Sciences, State Key Laboratory of Biomembrane and Membrane Biology, PKU-IDG/McGovern Institute For Brain Research, Beijing Advanced Innovation Center for Genomics, School of Life Sciences, Peking University, Beijing, China.
Guang YangPeking-Tsinghua Center for Life Sciences, State Key Laboratory of Biomembrane and Membrane Biology, PKU-IDG/McGovern Institute For Brain Research, Beijing Advanced Innovation Center for Genomics, School of Life Sciences, Peking University, Beijing, China.
Jiayun LiPeking-Tsinghua Center for Life Sciences, State Key Laboratory of Biomembrane and Membrane Biology, PKU-IDG/McGovern Institute For Brain Research, Beijing Advanced Innovation Center for Genomics, School of Life Sciences, Peking University, Beijing, China.
Rui XuSchool of Basic Medical Sciences, Nanjing Medical University, Nanjing, China.
Dandan ZhangSchool of Basic Medical Sciences, Nanjing Medical University, Nanjing, China.
Juan HuangSchool of Basic Medical Sciences, Nanjing Medical University, Nanjing, China.
Yi RaoPeking-Tsinghua Center for Life Sciences, State Key Laboratory of Biomembrane and Membrane Biology, PKU-IDG/McGovern Institute For Brain Research, Beijing Advanced Innovation Center for Genomics, School of Life Sciences, Peking University, Beijing, China.ORCID 0000-0002-0405-5426
Peking University · CNNanjing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Our understanding of the molecular mechanisms underlying sleep homeostasis is limited. We have taken a systematic approach to study neural signaling by the transmitter 5-hydroxytryptamine (5-HT) in drosophila. We have generated knockout and knockin lines for

Indexed as

HomeostasisSleepWakefulnessAnimalsDrosophila melanogasterDrosophila ProteinsGene Knock-In TechniquesGene Knockout TechniquesNeuronsReceptor, Serotonin, 5-HT2BDrosophila ProteinsReceptor, Serotonin, 5-HT2B5HT2b receptordFB neuronsD. melanogasterneuroscienceserotoninsleep homeostasis

Identifiers

PMID28984573
PMCPMC5648528
OpenAlexW2761616551

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.