ReviewTransboundary and emerging diseases2018
Fasciola and fasciolosis in ruminants in Europe: Identifying research needs.
Review in Transboundary and emerging diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 87 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
87 citing papers in PubMed, 3 syntheses or guidelines pooled it, 209 citations in OpenAlex.
- Prevalence and risk factors of sheep and goats fasciolosis in Ethiopia: A systematic review and meta-analysis.PLoS neglected tropical diseases · 2025Pooled it
- Susceptibility of lymnaeid snails toPeerJ · 2025Pooled it
- Increasing importance of anthelmintic resistance in European livestock: creation and meta-analysis of an open database.Parasite (Paris, France) · 2020Pooled it
- Novel environmental risk index reveals uneven impact of climate change on fascioliasis risk across Africa and Europe.PLoS neglected tropical diseases · 2026Article
- Host-parasite-microbiome interactions in gastrointestinal trematodes and cestodes of small ruminants: current advances and future perspectives.Veterinary research communications · 2026Review
- Single-cell transcriptomics identifies a p21-activated kinase important for survival of the zoonotic parasiteiScience · 2026Article
- Assessing the impact of Fasciola hepatica excretory-secretory antigens on A549 cells: viability, apoptosis, ROS, and stem cell markers.BMC research notes · 2026Article
- New insights into trematode infections in cattle and their snail intermediate hosts in a Mediterranean area of Italy.Food and waterborne parasitology · 2026Article
- Fasciola hepatica in alpine dairy farming: prevalence trends, risk factors and associations with Salmonella Dublin seropositivity.BMC veterinary research · 2026Article
- "Not a problem because we drench for it": the management of liver fluke on sheep farms.Frontiers in veterinary science · 2026Article
- Identification ofFrontiers in parasitology · 2026Article
- Timing ofFrontiers in immunology · 2026Article
- Pharmacokinetic barriers to oxfendazole flukicidal efficacy.PloS one · 2026Article
- Projected climate change effects on suitable habitat for Pseudosuccinea columella and Radix natalensis in uMgungundlovu, South Africa.PloS one · 2026Article
- Evaluation of Gastrointestinal Endoparasites in Cattle in Central Spain: Focus onPathogens (Basel, Switzerland) · 2025Article
- Evaluation ofVaccines · 2025Article
- Natural Infection byAnimals : an open access journal from MDPI · 2025Article
- Haematobiochemical Alterations and Pathological Lesions Induced by Fasciolosis in Slaughtered Cattle at Gondar ELFORA Abattoir, Northwest Ethiopia.Veterinary medicine and science · 2025Article
- Detection and prevalence of parasites in creole cattle from a rural area in an Andean district of Peru.Tropical animal health and production · 2025Article
- First report ofJournal of veterinary research · 2025Article
27 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 5 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fasciola hepatica is a trematode parasite with a global distribution, which is responsible for considerable disease and production losses in a range of food producing species. It is also identified by WHO as a re-emerging neglected tropical disease associated with endemic and epidemic outbreaks of disease in human populations. In Europe, F. hepatica is mostly associated with disease in sheep, cattle and goats. This study reviews the most recent advances in our understanding of the transmission, diagnosis, epidemiology and the economic impact of fasciolosis. We also focus on the impact of the spread of resistance to anthelmintics used to control F. hepatica and consider how vaccines might be developed and applied in the context of the immune-modulation driven by the parasite. Several major research gaps are identified which, when addressed, will contribute to providing focussed and where possible, bespoke, advice for farmers on how to integrate stock management and diagnosis with vaccination and/or targeted treatment to more effectively control the parasite in the face of increasing the prevalence of infection and spread of anthelmintic resistance that are likely to be exacerbated by climate change.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.