Evidence map›Paper›PMID 28984325›Full record

ArticleOrganic & biomolecular chemistry2017

Synthesis of kinase inhibitors containing a pentafluorosulfanyl moiety.

Supojjanee Sansook, Cory A Ocasio, Iain J Day, Graham J Tizzard, Simon J Coles, Oleg Fedorov, James M Bennett, Jonathan M Elkins, John Spencer

Erratum issuedOpen access · hybridAbstract read
In one paragraph

Article in Organic & biomolecular chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Supojjanee SansookDept of Chemistry, School of Life Sciences, University of Sussex, Falmer, BN1 9QJ, UK. j.spencer@sussex.ac.uk.
Cory A OcasioDept of Chemistry, School of Life Sciences, University of Sussex, Falmer, BN1 9QJ, UK. j.spencer@sussex.ac.uk.ORCID http://orcid.org/0000-0002-4957-4131
Iain J DayDept of Chemistry, School of Life Sciences, University of Sussex, Falmer, BN1 9QJ, UK. j.spencer@sussex.ac.uk.ORCID http://orcid.org/0000-0002-2311-6837
Graham J TizzardUK National Crystallography Service, Chemistry, University of Southampton, Highfield, Southampton, SO17 1BJ, UK.ORCID http://orcid.org/0000-0002-1577-5779
Simon J ColesUK National Crystallography Service, Chemistry, University of Southampton, Highfield, Southampton, SO17 1BJ, UK.ORCID http://orcid.org/0000-0001-8414-9272
Oleg FedorovStructural Genomics Consortium, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, OX3 7DQ, UK.
James M BennettStructural Genomics Consortium, Universidade Estadual de Campinas, Campinas, SP 13083-886, Brazil.
Jonathan M ElkinsStructural Genomics Consortium, Universidade Estadual de Campinas, Campinas, SP 13083-886, Brazil.ORCID http://orcid.org/0000-0003-2858-8929
John SpencerDept of Chemistry, School of Life Sciences, University of Sussex, Falmer, BN1 9QJ, UK. j.spencer@sussex.ac.uk.ORCID http://orcid.org/0000-0001-5231-8836
University of Sussex · GBUniversidade Estadual de Campinas (UNICAMP) · BRUniversity of Southampton · GBUniversity of Oxford · GB

Funding

Wellcome Trust
6 · The paper itself

Abstract

A series of 3-methylidene-1H-indol-2(3H)-ones substituted with a 5- or 6-pentafluorosulfanyl group has been synthesized by a Knoevenagel condensation reaction of SF

Indexed as

Cell LineCell ProliferationCrystallography, X-RayDose-Response Relationship, DrugFluoridesHumansIndolesModels, MolecularMolecular StructureOxindolesProtein Kinase InhibitorsProtein KinasesStructure-Activity RelationshipSulfur Compounds2-oxindoleFluoridesIndolesOxindolesProtein Kinase InhibitorsProtein KinasesSulfur Compoundssulfur pentafluoride cation

Identifiers

PMID28984325
PMCPMC5708334
OpenAlexW2760644379

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.