ReviewNature reviews. Neurology2017
PET imaging of the neurovascular interface in cerebrovascular disease.
Review in Nature reviews. Neurology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 55 citations in OpenAlex.
- PET Imaging of Carotid Atherosclerosis: Methodology, Implications, and Applications in Neurovascular Disease.Stroke · 2026Review
- Inflammation of central nervous system fiber tracts is active in patients over six months post-intracerebral hemorrhage.Acta neuropathologica communications · 2025Article
- Thrombus composition in ischaemic stroke: histological and radiological evaluation, and implications for acute clinical management.Journal of thrombosis and thrombolysis · 2025Review
- Brain perivascular macrophages: current understanding and future prospects.Brain : a journal of neurology · 2024Review
- In vivo Imaging of Cannabinoid Type 2 Receptors: Functional and Structural Alterations in Mouse Model of Cerebral Ischemia by PET and MRI.Molecular imaging and biology · 2022Article
- Brain Metabolic Network Redistribution in Patients with White Matter Hyperintensities on MRI Analyzed with an Individualized Index Derived fromKorean journal of radiology · 2022Article
- Crossed cerebellar diaschisis-related supratentorial hemodynamic and metabolic status measured by PET/MR in assessing postoperative prognosis in chronic ischemic cerebrovascular disease patients with bypass surgery.Annals of nuclear medicine · 2022Article
- Microglia and Stem-Cell Mediated Neuroprotection after Neonatal Hypoxia-Ischemia.Stem cell reviews and reports · 2022Review
- Imaging High-Risk Atherothrombosis Using a Novel Fibrin-Binding Positron Emission Tomography Probe.Stroke · 2022Article
- Advances in PET imaging of ischemic stroke.Frontiers in stroke · 2022Review
- Dual-model wearable photoacoustic microscopy and electroencephalograph: study of neurovascular coupling in anesthetized and freely moving rats.Biomedical optics express · 2021Article
- A narrative review of the pathophysiology of ischemic stroke in carotid plaques: a distinction versus a compromise between hemodynamic and embolic mechanism.Annals of translational medicine · 2021Review
- Imaging Biomarkers for Monitoring the Inflammatory Redox Landscape in the Brain.Antioxidants (Basel, Switzerland) · 2021Review
- Carotid Atheroinflammation Is Associated With Cerebral Small Vessel Disease Severity.Frontiers in neurology · 2021Article
- A variable resolution approach for improved acquisition of hyperpolarizedMagnetic resonance in medicine · 2020Article
- Nuclear medicine and molecular imaging advances in the 21st century.The British journal of radiology · 2020Review
- Interactions Between Tumor Biology and Targeted Nanoplatforms for Imaging Applications.Advanced functional materials · 2020Article
- MicroRNA-579-3p Exerts Neuroprotective Effects Against Ischemic Stroke via Anti-Inflammation and Anti-Apoptosis.Neuropsychiatric disease and treatment · 2020Article
- Patterns of Mitochondrial TSPO Binding in Cerebral Small Vessel Disease: AnFrontiers in neurology · 2020Article
- Neuroimaging Biomarkers for Alzheimer's Disease.Molecular neurodegeneration · 2019Review
Corrections and comments
- Erratum issued
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
Cerebrovascular disease encompasses a range of pathologies that affect different components of the cerebral vasculature and brain parenchyma. Large artery atherosclerosis, acute cerebral ischaemia, and intracerebral small vessel disease all demonstrate altered metabolic processes that are key to their pathogenesis. Although structural imaging techniques such as MRI are the mainstay of clinical care and research in cerebrovascular disease, they have limited ability to detect these pathophysiological processes in vivo. By contrast, PET can detect and quantify metabolic processes that are relevant to each facet of cerebrovascular disease. Information obtained from PET studies has helped to shape the understanding of key concepts in cerebrovascular medicine, including vulnerable atherosclerotic plaque, salvageable ischaemic penumbra, neuroinflammation and selective neuronal loss after ischaemic insult. PET has also helped to elucidate the relationships between chronic hypoxia, neuroinflammation, and amyloid-β deposition in cerebral small vessel disease. This Review describes how PET-based imaging of metabolic processes at the neurovascular interface has contributed to our understanding of cerebrovascular disease.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.