ArticleInfection and immunity1988
Mediation of immunity to Eimeria vermiformis in mice by L3T4+ T cells.
Article in Infection and immunity, 1988. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 66 citations in OpenAlex.
- Eimeria bovis infection enhances adhesion of peripheral blood mononuclear cells to and their transmigration through an infected bovine endothelial cell monolayer in vitro.Parasitology research · 2007Article
- Treatment of mice with the anticoccidial drug Toltrazuril does not interfere with the development of a specific cellular intestinal immune response to Eimeria falciformis.Parasitology research · 2005Article
- Age-dependent requirement for gammadelta T cells in the primary but not secondary protective immune response against an intestinal parasite.The Journal of experimental medicine · 2003Article
- Antigenic diversity in Eimeria maxima and the influence of host genetics and immunization schedule on cross-protective immunity.Infection and immunity · 2002Article
- An alphabeta T-cell-independent immunoprotective response towards gut coccidia is supported by gammadelta cells.Immunology · 2000Article
- Genetic dissection of primary and secondary responses to a widespread natural pathogen of the gut, Eimeria vermiformis.Infection and immunity · 2000Article
- Nonspecific immune responses and mechanisms of resistance to Eimeria papillata infections in mice.Infection and immunity · 1997Article
- Oral vaccination against coccidiosis: responses in strains of mice that differ in susceptibility to infection with Eimeria vermiformis.Infection and immunity · 1997Article
- T-cell alpha beta + and gamma delta + deficient mice display abnormal but distinct phenotypes toward a natural, widespread infection of the intestinal epithelium.Proceedings of the National Academy of Sciences of the United States of America · 1996Article
- Avian gut-associated lymphoid tissues and intestinal immune responses to Eimeria parasites.Clinical microbiology reviews · 1996Review
- Responses to vaccination in strains of mice that differ in susceptibility to coccidiosis.Infection and immunity · 1996Article
- Intestinal changes associated with expression of immunity to challenge with Eimeria vermiformis.Infection and immunity · 1992Article
- X-irradiation of Eimeria tenella oocysts provides direct evidence that sporozoite invasion and early schizont development induce a protective immune response(s).Infection and immunity · 1991Article
- New mouse models for chronic Cryptosporidium infection in immunodeficient hosts.Infection and immunity · 1990Article
- Parasite exposure elicits a preferential T-cell response involved in protective immunity against Eimeria species in chickens primed by an internal-image anti-idiotypic antibody.Infection and immunity · 1989Article
- Gamma interferon controls Eimeria vermiformis primary infection in BALB/c mice.Infection and immunity · 1989Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
Immunity to infection with Eimeria vermiformis was transferred in NIH mice by both the nylon wool-adherent (B-cell-enriched) and nonadherent (T-cell-enriched) fractions of lymphocytes (spleen and mesenteric lymph node) taken from infected donors. Transfer was more variable with the adherent fraction, and when contaminating T cells were removed by treatment with anti-Thy1 monoclonal antibody (MAb) and complement, this fraction lost all protective activity. The protective effect of T-cell-enriched populations of mesenteric lymphocytes was abrogated by treatment with anti-L3T4 MAb and complement in vitro before transfer or by opsonization with this MAb in vitro before intravenous inoculation into recipients. Similar treatments of cells with anti-Lyt2 MAb did not have this effect, confirming that Thy1+ L3T4+ cells mediate the adoptive transfer of immunity to E. vermiformis. Thy1+ L3T4+ cells were also shown to limit the replication of E. vermiformis in primary infections: mice depleted of this subset (by thymectomy followed by intravenous injection of anti-L3T4 MAb) passed greater numbers of oocysts over a longer period of time than did mice similarly depleted of Lyt2+ cells.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.