Evidence map›Paper›PMID 28984060›Full record

ReviewInternational journal of clinical practice2017

A practical approach to the management of nocturia.

Matthias Oelke, Stefan De Wachter, Marcus J Drake, Antonella Giannantoni, Mike Kirby, Susan Orme, Jonathan Rees, Philip van Kerrebroeck, Karel Everaert

Open access · hybridAbstract readReview
In one paragraph

Review in International journal of clinical practice, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 2 pooled it
13.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 2 syntheses or guidelines pooled it, 111 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Psychometric validation and interpretation of the Nocturia Impact Diary in a clinical trial setting.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022
    Trial
  4. Article
  5. Observational
  6. Article
  7. Article
  8. Article
  9. Diurnal regulation of urinary behavior and gene expression in aged mice.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025
    Article
  10. Article
  11. Nocturia and obstructive sleep apnoea.Nature reviews. Urology · 2024
    Review
  12. Sleep and home parenteral nutrition in adults: A narrative review.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2024
    Review
  13. Article
  14. Article
  15. 2024 Canadian Urological Association guideline: Female stress urinary incontinence.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2024
    Article
  16. Article
  17. Observational
  18. Article
  19. Canadian Urological Association best practice report: Diagnosis and management of nocturia.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 4 countries.

Matthias OelkeDepartment of Urology, University of Maastricht, Maastricht, The Netherlands.
Stefan De WachterDepartment of Urology, University of Antwerp, Antwerp, Belgium.
Marcus J DrakeDepartment of Urology, University of Bristol, Bristol, UK.
Antonella GiannantoniDepartment of Surgical and Biomedical Sciences, Urology and Andrology Unit, University of Perugia, Perugia, Italy.
Mike KirbyThe Centre for Research in Primary and Community Care, The University of Hertfordshire and The Prostate Centre, London, UK.ORCID http://orcid.org/0000-0002-5429-7714
Susan OrmeDepartment of Geriatric Medicine, Barnsley Hospital NHS Foundation Trust Hospital, Barnsley, UK.
Jonathan ReesBackwell and Nailsea, North Somerset, UK.
Philip van KerrebroeckDepartment of Urology, University of Maastricht, Maastricht, The Netherlands.
Karel EveraertDepartment of Urology, Ghent University Hospital, Ghent, Belgium.
Maastricht University · NLBarnsley Hospital NHS Foundation Trust · GBGhent University Hospital · BEUniversity of Antwerp · BEUniversity of Bristol · GBUniversity of Hertfordshire · GBUniversity of Perugia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo raise awareness on nocturia disease burden and to provide simplified aetiologic evaluation and related treatment pathways.

methodsA multidisciplinary group of nocturia experts developed practical advice and recommendations based on the best available evidence supplemented by their own experiences.

resultsNocturia is defined as the need to void ≥1 time during the sleeping period of the night. Clinically relevant nocturia (≥2 voids per night) affects 2%-18% of those aged 20-40 years, rising to 28%-62% for those aged 70-80 years. Consequences include the following: lowered quality of life; falls and fractures; reduced work productivity; depression; and increased mortality. Nocturia-related hip fractures alone cost approximately €1 billion in the EU and $1.5 billion in the USA in 2014. The pathophysiology of nocturia is multifactorial and typically related to polyuria (either global or nocturnal), reduced bladder capacity or increased fluid intake. Accurate assessment is predicated on frequency-volume charts combined with a detailed patient history, medicine review and physical examination. Optimal treatment should focus on the underlying cause(s), with lifestyle modifications (eg, reducing evening fluid intake) being the first intervention. For patients with sustained bother, medical therapies should be introduced; low-dose, gender-specific desmopressin has proven effective in nocturia due to idiopathic nocturnal polyuria. The timing of diuretics is an important consideration, and they should be taken mid-late afternoon, dependent on the specific serum half-life. Patients not responding to these basic treatments should be referred for specialist management.

conclusionsThe cause(s) of nocturia should be first evaluated in all patients. Afterwards, the underlying pathophysiology should be treated specifically, alone with lifestyle interventions or in combination with drugs or (prostate) surgery.

Indexed as

Antidiuretic AgentsDeamino Arginine VasopressinHumansLife StyleNocturiaPolyuriaQuality of LifeAntidiuretic AgentsDeamino Arginine Vasopressinassessment of healthcare needsdesmopressinexpert opinionmorbiditymortalitynocturiapathophysiology

Identifiers

PMID28984060
PMCPMC5698733
OpenAlexW2761288185

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.