Evidence map›Paper›PMID 28983843›Full record

ArticleMolecular neurobiology2018

Kefu Liu, Jinlong Yu, Juan Zhao, Yanhong Zhou, Nian Xiong, Jie Xu, Tao Wang, Richard L Bell, Hong Qing, Zhicheng Lin

Abstract read
In one paragraph

Article in Molecular neurobiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Kefu LiuLaboratory of Psychiatric Neurogenomics, Division of Basic Neuroscience, Mailman Neuroscience Research Center, McLean Hospital, Belmont, MA, 02478, USA.
Jinlong YuLaboratory of Psychiatric Neurogenomics, Division of Basic Neuroscience, Mailman Neuroscience Research Center, McLean Hospital, Belmont, MA, 02478, USA.
Juan ZhaoLaboratory of Psychiatric Neurogenomics, Division of Basic Neuroscience, Mailman Neuroscience Research Center, McLean Hospital, Belmont, MA, 02478, USA.
Yanhong ZhouLaboratory of Psychiatric Neurogenomics, Division of Basic Neuroscience, Mailman Neuroscience Research Center, McLean Hospital, Belmont, MA, 02478, USA.
Nian XiongLaboratory of Psychiatric Neurogenomics, Division of Basic Neuroscience, Mailman Neuroscience Research Center, McLean Hospital, Belmont, MA, 02478, USA.
Jie XuDepartment of Computer Information Systems, Bentley University, Waltham, MA, 02452, USA.
Tao WangDepartment of Neurology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430074, China.
Richard L BellDepartment of Psychiatry, Institute of Psychiatric Research, Indiana University School of Medicine, Indianapolis, IN, 46202, USA.
Hong QingSchool of Life Science, Beijing Institute of Technology, Beijing, 100081, China.
Zhicheng LinLaboratory of Psychiatric Neurogenomics, Division of Basic Neuroscience, Mailman Neuroscience Research Center, McLean Hospital, Belmont, MA, 02478, USA. zhicheng_lin@hms.harvard.edu.ORCID http://orcid.org/0000-0003-1372-422X
Beijing Institute of Technology · CNHarvard University · USUnion Hospital · CNBentley University · USIndiana University School of Medicine

Funding

Translational Research and Science Education (OUT)P60AA007611 · NIAAA · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI Marian Lee Logrip · 2003 to 2026
$45.5M
Human dopamine transporter gene: variations and transcriptional regulationR01DA021409 · NIDA · MCLEAN HOSPITAL · PI LIN, ZHICHENG CARL · 2007 to 2024
$4.9M
Rat Animal Models Core (RAMC)U01AA013522 · NIAAA · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI BELL, RICHARD LOWELL · 2001 to 2014
$4.3M
Rodents with Genetic Differences in Alcohol PreferenceU24AA015512 · NIAAA · INDIANA UNIVERSITY INDIANAPOLIS · PI BELL, RICHARD LOWELL · 2015 to 2019
$2.7M
Rat Animal Models & Drug and Gene Testing Core (RAM-DGTC)U24AA013522 · NIAAA · INDIANA UNIVERSITY INDIANAPOLIS · PI BELL, RICHARD LOWELL · 2015 to 2021
$2.4M
NIAAA NIH HHS P60 AA007611NIAAA NIH HHS U01 AA013522NIAAA NIH HHS U24 AA013522NIAAA NIH HHS U24 AA015512NIDA NIH HHS DA021409NIDA NIH HHS R01 DA021409
6 · The paper itself

Abstract

Regulated activity of SLC6A3, which encodes the human dopamine transporter (DAT), contributes to diseases such as substance abuse disorders (SUDs); however, the exact transcription mechanism remains poorly understood. Here, we used a common genetic variant of the gene, intron 1 DNP1B sequence, as bait to screen and clone a new transcriptional activity,

Indexed as

Epistasis, Genetic3' Untranslated RegionsAdaptor Proteins, Signal TransducingAllelesCell LineCell NucleusDopamine Plasma Membrane Transport ProteinsDopaminergic NeuronsDown-RegulationHumansPromoter Regions, GeneticSubstance-Related Disorders3' Untranslated RegionsAdaptor Proteins, Signal TransducingAZI2 protein, humanDopamine Plasma Membrane Transport ProteinsSLC6A3 protein, humanAllele-dependentDopamine transporterKangaroo layout of geneslncRNARibonucleic repressorTranscription factor

Identifiers

PMID28983843
PMCPMC5886844
OpenAlexW2763311907

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.