ArticleEuropean child & adolescent psychiatry2018
Clinical factors associated with decision to recommend methylphenidate treatment for children with ADHD in France.
Article in European child & adolescent psychiatry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 14 citations in OpenAlex.
- Treatments with versus without medication for children with behavioural difficulties in clinical practice: an economic evaluation with observational data.Journal of child psychology and psychiatry, and allied disciplines · 2025Observational
- Paternal intelligence affects school grades in children with and without ADHD - a register-based study.European child & adolescent psychiatry · 2025Article
- Patterns of Response to Methylphenidate Administration in Children with ADHD: A Personalized Medicine Approach through Clustering Analysis.Children (Basel, Switzerland) · 2021Article
- Maternal Sociodemographic Factors Are Associated with Methylphenidate Initiation in Children in the Netherlands: A Population-Based Study.Child psychiatry and human development · 2021Article
- Child and Parental Characteristics of Medication Use for Attention-Deficit/Hyperactivity Disorder.Journal of child and adolescent psychopharmacology · 2020Article
- Individualizing the dosage of Methylphenidate in children with attention deficit hyperactivity disorder.BMC medical research methodology · 2020Article
- Barriers and predictors of medication use for childhood ADHD: findings from a UK population-representative cohort.Social psychiatry and psychiatric epidemiology · 2019Article
- Towards a better understanding of the many facets of attention-deficit/hyperactivity disorder.European child & adolescent psychiatry · 2018Article
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
European guidelines advise on best practices for the diagnosis and non-pharmacological and pharmacological treatment of attention-deficit hyperactivity disorder (ADHD). This study aimed to (1) assess whether clinician's decisions to initiate methylphenidate treatment in children diagnosed with ADHD are in accordance with European guidelines and (2) identify clinical factors associated with the decision to recommend methylphenidate prescription. 5 to 13-year-old patients with an ADHD diagnosis were consecutively evaluated in an outpatient child and adolescent psychiatry clinic in France. Patients underwent a multidisciplinary evaluation including a diagnostic interview, symptom severity assessments with parent questionnaires, and IQ testing. We compared children with (n = 105) and without (n = 55) recommended methylphenidate treatment using Student's t test or Wilcoxon Mann-Whitney test and Chi-square or Fisher's test. Multivariate logistic regression was implemented to determine the respective influence of each variable on treatment recommendation. Recommendation to initiate methylphenidate treatment was associated with (1) ADHD combined presentation, (2) co-occurring Oppositional Defiant Disorder/Conduct Disorder (ODD/CD), Developmental Coordination Disorder (DCD) and Learning Disorder (LD), (3) clinical severity and impairment indicated on parent questionnaires, and (4) reduced perceptual reasoning. Using a multivariate regression model, ADHD combined presentation [combined versus predominantly hyperactive/impulsive and unspecified OR 4.52 (1.23-16.55), p = 0.023], age [OR 1.46 (1.14-1.88), p = 0.003], ODD/CD [OR 5.53 (2.19-14.01), p < 0.001], DCD [OR 4.22 (1.70-10.48), p = 0.002], PRI [OR 0.97 (0.94-0.99), p = 0.01] were significantly associated with recommendation of methylphenidate treatment. Our results indicate that clinicians' treatment decision-making complies with European guidelines and is furthermore associated with the type and severity of ADHD symptoms but also with co-occurring disorders.
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