ArticleLangenbeck's archives of surgery2017
The distribution of lymph node metastases and their size in colon cancer.
Article in Langenbeck's archives of surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.
- Complete mesocolic excision for right hemicolectomy: an updated systematic review and meta-analysis.Techniques in coloproctology · 2023Pooled it
- Novel scoring system for the preoperative computed tomographic diagnosis of lymph node metastasis in colorectal cancer patients.Surgery today · 2026Article
- Current Status and Challenges of Imaging-Based Diagnosis of Lymph Node Metastasis in Colon Cancer: The Lymph Node Committee of the Japanese Society for Cancer of the Colon and Rectum.Annals of gastroenterological surgery · 2026Review
- Complete mesocolon excision versus conventional colectomy for resectable colon cancer.The Cochrane database of systematic reviews · 2025Article
- Multidimensional differences of right- and left-sided colorectal cancer and their impact on targeted therapies.NPJ precision oncology · 2025Review
- MRI radiomic study on prediction of nonenlarged lymph node metastasis of rectal cancer: reduced field-of-view versus conventional DWI.European radiology experimental · 2025Article
- Preoperative CT lymph node size as a predictor of nodal metastasis in resectable Colon cancer: a retrospective study of 694 patients.BMC gastroenterology · 2025Article
- Optimal extent of lymph node dissection in clinical early-stage right colon cancer: a retrospective analysis.Annals of surgical treatment and research · 2025Article
- Development and validation of machine learning-based MRI radiomics models for preoperative lymph node staging in T3 rectal cancer.Frontiers in oncology · 2025Article
- Proposal for standardization of laparoscopic D3 lymphadenectomy for right colon cancer.Techniques in coloproctology · 2024Observational
- A nomogram with Nottingham prognostic index for predicting locoregional recurrence in breast cancer patients.Frontiers in oncology · 2024Article
- Best Evidence for Each Surgical Step in Minimally Invasive Right Hemicolectomy: A Systematic Review.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2023Review
- CT morphological features for predicting the risk of lymph node metastasis in T1 colorectal cancer.European radiology · 2023Article
- A novel web-based dynamic nomogram for recurrent laryngeal nerve lymph node metastasis in esophageal squamous cell carcinoma.Frontiers in surgery · 2022Article
- Follistatin-Like 3 Correlates With Lymph Node Metastasis and Serves as a Biomarker of Extracellular Matrix Remodeling in Colorectal Cancer.Frontiers in immunology · 2021Article
- Which is more important in the management of splenic flexure colon cancer: strict central lymph node dissection or adequate bowel resection margin?Techniques in coloproctology · 2020Article
- Contrast-enhanced CT imaging for the assessment of lymph node status in patients with colorectal cancer.Oncology letters · 2020Article
- Can factors that influence nodal dissemination in patients with colorectal cancer be identified? Own experience.Przeglad gastroenterologiczny · 2020Article
- Preoperative inflammatory response as prognostic factor of patients with colon cancer.Langenbeck's archives of surgery · 2019Article
- Novel nomograms to predict lymph node metastasis and liver metastasis in patients with early colon carcinoma.Journal of translational medicine · 2019Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe purpose of this study is to clarify the optimal extent of lymph node dissection for colon cancer by evaluating the distributions of lymph node metastases and lymph node size according to tumor location and T stage.
methodsThis study enrolled 662 patients who underwent curative resection for primary colon cancer between 2013 and 2015. Lymph node regions were classified into pericolic, intermediate, and main nodes. The short-axis diameter of each dissected lymph node was measured. The distributions of lymph node metastases and lymph node size were evaluated according to tumor location and T stage.
resultsIn the overall cohort, the incidence of metastases in pericolic nodes located more than 5 cm but no more than 10 cm from tumor and in pericolic nodes located more than 10 cm from tumor was 3.6 and 0.2%, respectively. More than 2% of patients with ≥ T2 tumor had metastases in main lymph nodes, and no patients with T1 tumor had metastases in main lymph nodes. Only 0.7% of patients with T1 tumor had lymph node metastases in pericolic nodes located more than 5 cm from the tumor. Both metastatic and non-metastatic lymph node sizes were significantly larger in right-sided colon cancer than in left-sided colon cancer, and both metastatic and non-metastatic lymph node sizes were significantly larger in ≥ T2 tumor than in T1 tumor.
conclusionIt is necessary to resect 10 cm of normal bowel both proximal and distal to the tumor and to perform D3 lymph node dissection for ≥ T2 colon cancer.
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