Evidence map›Paper›PMID 28983752›Full record

ArticleCytotechnology2018

Cytotoxicity and apoptotic cell death induced by Vitis vinifera peel and seed extracts in A431 skin cancer cells.

J Grace Nirmala, S Evangeline Celsia, Akila Swaminathan, R T Narendhirakannan, Suvro Chatterjee

Open access · bronzeAbstract read
In one paragraph

Article in Cytotechnology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 47 citations in OpenAlex.

  1. Plant Extracts as Modulators of the Wound Healing Process-Preliminary Study.International journal of molecular sciences · 2025
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  5. Antioxidant and Anticancer Activity ofLife (Basel, Switzerland) · 2024
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  9. Antiviral Activity ofViruses · 2021
    Article
  10. Article
  11. Grapevine as a Rich Source of Polyphenolic Compounds.Molecules (Basel, Switzerland) · 2020
    Review
  12. Review
  13. Pharmaceuticals (Basel, Switzerland) · 2020
    Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

J Grace NirmalaDepartment of Biotechnology, School of Biotechnology and Health Sciences, Karunya University (Karunya Institute of Technology and Sciences), Karunya Nagar, Coimbatore, Tamil Nadu, 641 114, India.
S Evangeline CelsiaDepartment of Biotechnology, School of Biotechnology and Health Sciences, Karunya University (Karunya Institute of Technology and Sciences), Karunya Nagar, Coimbatore, Tamil Nadu, 641 114, India.
Akila SwaminathanAU-KBC Research Centre and Department of Biotechnology, Anna University, Chennai, India.
R T NarendhirakannanDepartment of Biotechnology, School of Biotechnology and Health Sciences, Karunya University (Karunya Institute of Technology and Sciences), Karunya Nagar, Coimbatore, Tamil Nadu, 641 114, India. bionaren_phd@yahoo.co.in.
Suvro ChatterjeeAU-KBC Research Centre and Department of Biotechnology, Anna University, Chennai, India.
Karunya University · INAnna University, Chennai · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vitis vinifera. L is one of the most widely consumed fruits in the world and are rich in antioxidant abundant polyphenols. The present study was carried out to assess the antiproliferative and apoptotic effects of Vitis vinifera peel and seed extracts in an in vitro model using human epidermoid carcinoma A431 cell lines. Vitis vinifera peel and seed extracts were incubated with A431 cells to evaluate the antiproliferative, apoptotic effects and the morphological apoptotic changes induced by the extracts. Mitochondrial membrane potential was also measured after incubating the cells with extracts. At the inhibitory concentration (IC

Indexed as

ApoptosisCell deathPolyphenolsReactive oxygen speciesVitis vinifera

Identifiers

PMID28983752
PMCPMC5851950
OpenAlexW2763053600

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.