ArticleJournal of behavioral medicine2018
Cancer-related loneliness mediates the relationships between social constraints and symptoms among cancer patients.
Article in Journal of behavioral medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
43 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Social media-based interventions for patients with cancer: a meta-analysis and meta-regression of randomised controlled trials.Journal of cancer survivorship : research and practice · 2023Pooled it
- Overseas Care and Cancer Survivorship in Small Island Developing States of the Eastern Caribbean: Protocol for a Multicountry Mixed Methods Study (CaSIDEC Study).JMIR research protocols · 2026Article
- Decision regret in patients with rectal cancer undergoing multimodal therapy.Clinical and translational radiation oncology · 2026Article
- Parental Psychological Profiles in Autism and Other Developmental Contexts: A Latent Profile Analysis Informing Coordinated Family-Centered Care.Children (Basel, Switzerland) · 2026Article
- Factors associated with serious psychological distress among US adult cancer survivors: a cross-sectional observational analysis of the 2024 National Health Interview Survey.Journal of cancer survivorship : research and practice · 2026Article
- Article
- Training and Recruitment to Implement the CASA Psychosocial Intervention in Cancer Care.International journal of environmental research and public health · 2026Article
- The association between loneliness and quality of life in cancer survivors: All of Us research program.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Article
- Developing and validating a functional social relationships enhancement program for cancer patients: A Delphi method.Journal of education and health promotion · 2026Article
- Loneliness within couples coping with cancer: prevalence, associations with physical and mental health, and potential benefits of dyadic exercise.Frontiers in aging · 2026Article
- Social wellbeing in older breast cancer survivors taking adjuvant endocrine therapy: impacts of self-efficacy for symptom management and pain.Frontiers in aging · 2026Article
- Evaluating the psychosocial effects of cancer on sleep quality and mental health in elderly populations.BMC psychiatry · 2025Article
- Companionship and Sharing Create Social Connections of an Online Community-Based Intervention for Patients with Cancer Receiving Outpatient Care: Pilot Study.JMIR cancer · 2025Article
- Financial toxicity and quality of life among older adults with cancer: a moderated mediation model of loneliness and social support.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- The relationship between suffering, loneliness, social interaction, and perceived symptoms in advanced cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Observational
- Enhancing Communication Among Patients with Cancer, Caregivers, and Extended Family: Development of a Communication Module.International journal of environmental research and public health · 2025Review
- Influence of symptom burden on social alienation in lung cancer patients receiving chemotherapy: the chain mediating effect of perceived social support and positive psychological capital.BMC psychology · 2025Article
- Comparative analysis of hormonal therapy in low-grade endometrial stromal sarcoma: A retrospective study.Gynecologic oncology · 2024Article
- Factors Influencing Social Isolation among Cancer Patients: A Systematic Review.Healthcare (Basel, Switzerland) · 2024Review
- Factors associated with loneliness in middle-aged and older patients with breast cancer.Asia-Pacific journal of oncology nursing · 2024Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Cancer patients have high rates of persistent and disabling symptoms. Evidence suggests that social constraints (e.g., avoidance and criticism) negatively impact symptoms, but pathways linking these variables have yet to be identified. This study examined whether cancer-related loneliness (i.e., feeling socially disconnected related to having cancer) mediated the relationships between social constraints and symptoms (i.e., pain interference, fatigue, sleep disturbance, and cognitive complaints) in patients with various cancers (N = 182). Patients (51% female, mean age = 59) were recruited from the Indiana Cancer Registry and completed questionnaires assessing social constraints, cancer-related loneliness, and symptoms. Structural equation modeling was used to evaluate the hypothesized relationships among variables. The model demonstrated good fit. Consistent with our hypothesis, cancer-related loneliness mediated the relationships between social constraints and each symptom. Findings suggest that addressing cancer-related loneliness in symptom management interventions may mitigate the negative impact of social constraints on outcomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.