ArticleNeurosurgical review2018
Symptomatic and silent cerebral infarction following surgical clipping of unruptured intracranial aneurysms: incidence, risk factors, and clinical outcome.
Article in Neurosurgical review, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Neurocognitive outcomes after treatment of unruptured anterior communicating artery aneurysms - a systematic review.Neurosurgical review · 2026Pooled it
- Frailty and Severe White Matter Lesions Are Risk Factors for Surgical Treatment for Unruptured Cerebral Aneurysm in Older Adults.Neurologia medico-chirurgica · 2026Article
- Flow Diverter Implantation for Intracranial Aneurysm with Concomitant Cerebral Infarction in the Chronic Phase: A 3-Year Complete Obliteration Case.The American journal of case reports · 2025Article
- Risk factors and the role of intraoperative hypotension in cerebral infarction after microsurgical clipping of intracranial aneurysms: a retrospective case-control study.Neurosurgical review · 2025Article
- Improved rates of postoperative ischemia, completeness of aneurysm occlusion and neurological deficits in elective clipping of anterior circulation aneurysms over the past 20 years - association with technical improvements.Acta neurochirurgica · 2024Article
- The mechanism and therapy of aortic aneurysms.Signal transduction and targeted therapy · 2023Review
- Cerebral ischemia after treatment of posterior communicating artery aneurysms: clipping versus coiling.BMC neurology · 2022Article
- Utility of evoked potentials during anterior cerebral artery and anterior communicating artery aneurysm clipping.Clinical neurophysiology practice · 2022Article
- Detection of impending perfusion deficits by intraoperative computed tomography (iCT) in aneurysm surgery of the anterior circulation.Acta neurochirurgica · 2021Article
- Intraoperative indocyanine green video angiography (ICG-VA) with FLOW 800 software in complex intracranial aneurysm surgery.Chinese neurosurgical journal · 2021Article
- Acute ischemic stroke due to unruptured small aneurysm of internal carotid artery: A case report.Medicine · 2020Article
- Effects of Arteriovenous Thrombolysis Combined with Mechanical Thrombectomy on Efficacy and Neurological Function of Acute Cerebral Infarct Patients.BioMed research international · 2020Article
- Clipping versus coiling in unruptured anterior cerebral circulation aneurysms.Surgical neurology international · 2020Article
- Clinical features and outcomes of PComA aneurysms originating from fetal posterior communicating arteries in a single institution.Chinese neurosurgical journal · 2020Article
- Rare and Low-Frequency Variant ofCirculation. Genomic and precision medicine · 2018Article
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9 authors.
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Abstract
Cerebral infarction (CI) associated with clipping of unruptured intracranial aneurysms (UIAs) has not been completely studied. The role of individual and operative characteristics is not known, and the risk of silent CI has not been well described. To determine the incidence, risk factors, and clinical outcome of postoperative CI, we retrospectively analyzed 388 consecutive patients undergoing clipping of UIAs between January 2012 and December 2015. We reviewed the pre- and postoperative computed tomography (CT) images of each patient. Postoperative CI was defined as a new parenchymal hypodensity in the vascular territory of treated artery. Patient-specific, aneurysm-specific, and operative variables were analyzed as potential risk factors. Functional outcome at discharge was assessed with the modified Rankin Scale (mRS). Postoperative CI was found in 49 (12.6%) patients, 29 of whom manifested neurological deficits. The incidences of symptomatic stroke and silent CI were 7.5 and 5.2%, respectively. Multivariate analysis showed that larger aneurysm size and history of hypertension were significantly associated with CI. Disability (mRS > 2) rate was 42.9% among patients with CI, which was substantially higher than that among patients without (0.9%). In conclusion, the incidence of CI following clipping of UIAs was not low. Larger aneurysm size and history of hypertension were independent risk factors. Postoperative symptomatic stroke correlated with an extremely high risk of disability. Silent CI was seemingly nondisabling, but the possible cognitive consequence is pending.
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