Evidence map›Paper›PMID 28983523›Full record

ArticleACS omega2017

Glycoamino Acid Analogues of the Thomsen-Friedenreich Tumor-Associated Carbohydrate Antigen: Synthesis and Evaluation of Novel Antiproliferative Factor Glycopeptides.

Maqbool A Siddiqui, Shailesh Ambre, Susan K Keay, Jeffrey M Rhyne, Chen-Ou Zhang, Joseph J Barchi

Open access · goldAbstract read
In one paragraph

Article in ACS omega, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Synthetic Access to Fluorinated Analogs of a KnownACS organic & inorganic Au · 2026
    Article
  2. Synthesis of Fluorinated Glycotope Mimetics Derived fromInternational journal of molecular sciences · 2025
    Article
  3. Synthesis ofTetrahedron letters · 2021
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Maqbool A SiddiquiChemical Biology Laboratory, Center for Cancer Research, National Cancer Institute at Frederick, Frederick, Maryland 21702, United States.
Shailesh AmbreChemical Biology Laboratory, Center for Cancer Research, National Cancer Institute at Frederick, Frederick, Maryland 21702, United States.
Susan K KeayMedical Service, Veterans Administration Maryland Health Care System, Baltimore, Maryland 21201, United States.
Jeffrey M RhyneDepartment of Medicine and Department of Pathology, University of Maryland School of Medicine, Baltimore, Maryland 21201, United States.
Chen-Ou ZhangDepartment of Medicine and Department of Pathology, University of Maryland School of Medicine, Baltimore, Maryland 21201, United States.
Joseph J BarchiChemical Biology Laboratory, Center for Cancer Research, National Cancer Institute at Frederick, Frederick, Maryland 21702, United States.
Frederick National Laboratory for Cancer Research · USUniversity of Maryland, Baltimore · USInstitutes for Behavior Resources · US

Funding

A Glycopeptide from Interstitial Cystitis Patients as a Novel Anticancer LeadZIABC011232 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI BARCHI, JOSEPH JOHN · 2009 to 2024
$7.1M
6 · The paper itself

Abstract

Glycoamino acid analogues of the Thomsen-Friedenreich antigen disaccharide, where the 4' and 4″ hydroxyl groups were substituted with fluorine or hydrogen, were synthesized and incorporated into the asialylated antiproliferative factor (

Identifiers

PMID28983523
PMCPMC5623948
OpenAlexW2752543270

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.