ArticleCurrent opinion in systems biology2017
Topological methods for genomics: present and future directions.
Article in Current opinion in systems biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed.
- TopClust: Topological-based analysis of scRNA-seq data for data-driven identification of clusters and core cluster cells.Biophysical journal · 2026Article
- Relational Persistent Homology for Multispecies Data with Application to the Tumor Microenvironment.Bulletin of mathematical biology · 2024Article
- A primer on correlation-based dimension reduction methods for multi-omics analysis.Journal of the Royal Society, Interface · 2023Review
- An analysis modality for vascular structures combining tissue-clearing technology and topological data analysis.Nature communications · 2022Article
- Evolving Perspective on the Origin and Diversification of Cellular Life and the Virosphere.Genome biology and evolution · 2022Review
- Article
- From calcium imaging to graph topology.Network neuroscience (Cambridge, Mass.) · 2022Review
- The topology of data: opportunities for cancer research.Bioinformatics (Oxford, England) · 2021Article
- Classification of apatite structures via topological data analysis: a framework for a 'Materials Barcode' representation of structure maps.Scientific reports · 2021Article
- Identification of stem cells from large cell populations with topological scoring.Molecular omics · 2021Article
- Spatial topological analysis of sympathetic neurovascular characteristic of acupoints in Ren meridian using advanced tissue-clearing and near infrared II imaging.Computational and structural biotechnology journal · 2021Article
- Identification of relevant genetic alterations in cancer using topological data analysis.Nature communications · 2020Article
- The 2019 mathematical oncology roadmap.Physical biology · 2019Review
- Signal enrichment with strain-level resolution in metagenomes using topological data analysis.BMC genomics · 2019Article
- Topological gene expression networks recapitulate brain anatomy and function.Network neuroscience (Cambridge, Mass.) · 2019Article
- Precision Medicine for Acute Kidney Injury (AKI): Redefining AKI by Agnostic Kidney Tissue Interrogation and Genetics.Seminars in nephrology · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
Topological methods are emerging as a new set of tools for the analysis of large genomic datasets. They are mathematically grounded methods that extract information from the geometric structure of data. In the last few years, applications to evolutionary biology, cancer genomics, and the analysis of complex diseases have uncovered significant biological results, highlighting their utility for fulfilling some of the current analytic needs of genomics. In this review, the state of the art in the application of topological methods to genomics is summarized, and some of the present limitations and possible future developments are reviewed.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.