ArticleFrontiers in neuroscience2017
Unique Neural Characteristics of Atypical Lateralization of Language in Healthy Individuals.
Article in Frontiers in neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 30 citations in OpenAlex.
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- Does white matter structure relate to hemispheric language lateralization? A systematic review.Brain communications · 2026Review
- Brain white matter microstructural changes in chemotherapy-treated older long-term breast cancer survivors.Cancer medicine · 2024Article
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- Cortical thinning in chemotherapy-treated older long-term breast cancer survivors.Brain imaging and behavior · 2023Article
- Physical Education with Eduball Stimulates Non-Native Language Learning in Primary School Students.International journal of environmental research and public health · 2022Article
- Context-sensitive computational mechanistic explanation in cognitive neuroscience.Frontiers in psychology · 2022Review
- An updated investigation of the multidimensional structure of language lateralization in left- and right-handed adults: a test-retest functional transcranial Doppler sonography study with six language tasks.Royal Society open science · 2021Article
- Physical Activity With Eduball Stimulates Graphomotor Skills in Primary School Students.Frontiers in psychology · 2021Article
- Developmental Dynamic Dysphasia: Are Bilateral Brain Abnormalities a Signature of Inefficient Neural Plasticity?Frontiers in human neuroscience · 2020Article
- The Impact of Handedness, Sex, and Cognitive Abilities on Left-Right Discrimination: A Behavioral Study.Frontiers in psychology · 2018Article
- Article
- Power spectral analysis can determine language laterality from resting-state functional MRI data in healthy controls.Journal of neuroimaging : official journal of the American Society of NeuroimagingArticle
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Using functional magnetic resonance imaging (fMRI) in 63 healthy participants, including left-handed and ambidextrous individuals, we tested how atypical lateralization of language-i. e., bilateral or right hemispheric language representation-differs from the typical left-hemisphere dominance. Although regardless of their handedness, all 11 participants from the atypical group engaged classical language centers, i.e., Broca's and Wernicke's areas, the right-hemisphere components of the default mode network (DMN), including the angular gyrus and middle temporal gyrus, were also critically involved during the verbal fluency task. Importantly, activity in these regions could not be explained in terms of mirroring the typical language pattern because left-hemisphere dominant individuals did not exhibit similar significant signal modulations. Moreover, when spatial extent of language-related activity across whole brain was considered, the bilateral language organization entailed more diffuse functional processing. Finally, we detected significant differences between the typical and atypical group in the resting-state connectivity at the global and local level. These findings suggest that the atypical lateralization of language has unique features, and is not a simple mirror image of the typical left hemispheric language representation.
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