ArticleEye (London, England)2017
Application of OCT-angiography to characterise the evolution of chorioretinal lesions in acute posterior multifocal placoid pigment epitheliopathy.
Article in Eye (London, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 75 citations in OpenAlex.
- Article
- Changes in optical coherence tomography (OCT) parameters in follow-up of acute posterior multifocal placoid pigment epitheliopathy (APMPPE).International ophthalmology · 2025Article
- Multi-Wavelength Autofluorescence Characteristics and Association With Inflammation in Acute Posterior Multifocal Placoid Pigment Epitheliopathy.Investigative ophthalmology & visual science · 2025Article
- Acute Posterior Multifocal Placoid Pigment Epitheliopathy: Clinical and Iconographical Aspects of Two Cases.Cureus · 2025Article
- Immune pathogenic response landscape of acute posterior multifocal placoid pigment epitheliopathy revealed by scRNA sequencing.Genes and immunity · 2025Article
- Multimodal Imaging of a Case of Monitoring of Acute Posterior Multifocal Placoid Pigment Epitheliopathy (APMPPE): Long-Term Follow-Up.Case reports in ophthalmological medicine · 2025Article
- Vessel density on optical coherence tomography angiography is prognostic for future disease course in intermediate uveitis.Scientific reports · 2024Article
- OCT Angiography in Noninfectious Uveitis: A Description of Five Cases and Clinical Applications.Diagnostics (Basel, Switzerland) · 2023Article
- Case Report: Spectrum of interesting ocular manifestations following COVID-19 vaccination: a case series of real-world presentations.Frontiers in cellular and infection microbiology · 2023Article
- Benefits and Limitations of OCT-A in the Diagnosis and Follow-Up of Posterior Intraocular Inflammation in Current Clinical Practice: A Valuable Tool or a Deceiver?Diagnostics (Basel, Switzerland) · 2022Article
- Case Report: Acute Posterior Multifocal Placoid Pigment Epitheliopathy after SARS-CoV-2 Vaccination.Optometry and vision science : official publication of the American Academy of Optometry · 2022Article
- Coarsening of choriocapillaris on optical coherence tomography angiography as a sign of acute idiopathic blind spot enlargement.American journal of ophthalmology case reports · 2022Article
- Acute posterior multifocal placoid pigment epitheliopathy (APMPPE).Journal of ophthalmic inflammation and infection · 2021Review
- Automated Quantification of Choriocapillaris Lesion Area in Patients With Posterior Uveitis.American journal of ophthalmology · 2021Observational
- Classification Criteria for Acute Posterior Multifocal Placoid Pigment Epitheliopathy.American journal of ophthalmology · 2021Article
- Swept source OCTA reveals a link between choriocapillaris blood flow and vision loss in a case of tubercular serpiginous-like choroiditis.American journal of ophthalmology case reports · 2021Article
- Choroidal Vascular Changes in Acute Idiopathic Maculopathy as Demonstrated by Multimodal Imaging including Optical Coherence Tomography Angiography.Case reports in ophthalmological medicine · 2021Article
- Management of Acute Posterior Multifocal Placoid Pigment Epitheliopathy (APMPPE): Insights from Multimodal Imaging with OCTA.Case reports in ophthalmological medicine · 2020Article
- Optical Coherence Tomography Angiography in Eyes with Non-infectious Posterior Uveitis; Some Practical Aspects.Medical hypothesis, discovery & innovation ophthalmology journal · 2019Review
- Acute Posterior Multifocal Placoid Pigment Epitheliopathy Sharing Characteristic OCT Findings of Vogt-Koyanagi-Harada Disease.Case reports in ophthalmological medicine · 2019Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
PurposeThe aim of this study was to determine a sequence of structural changes in acute posterior multifocal placoid pigment epitheliopathy (APMPPE) using optical coherence tomography-angiography (OCT-A) and comparing with other imaging modalities.Patients and methodsPatients with a new diagnosis of acute-onset APMPPE referred to a regional specialist centre from October 2015 to October 2016 were included. Multimodal imaging employed on all patients from diagnosis included the following: fundus fluorescein angiography, indocyanine green angiography, fundus autofluorescence, spectral domain-OCT (SD-OCT), and OCT-A. All non-invasive imaging processes were repeated during follow-up.ResultsTen eyes of five patients were included in the study, three males and two females, with a mean age of 26.2 years (range: 21-32) and a mean follow-up of 6.4 months (range: 2.6-13.3). All patients presented with bilateral disease and macular involving lesions. OCT-A imaging of the choriocapillaris was supportive of hypoperfusion at the site of APMPPE lesions during the acute phase of this condition with normalisation of choroidal vasculature during follow-up. Multimodal imaging consistently highlighted four sequential phases from presentation to resolution of active disease.ConclusionsMultimodal imaging in patients with APMPPE in acute and long-term follow-up demonstrates a reversible choroidal hypoperfusion supporting the primary inciting pathology as a choriocapillaritis. The evolution shows resolution of the ischaemia through a defined sequence that results in persistent changes at the level of the retinal pigment epithelium and outer retina. OCT-A was able to detect preclinical changes and chart resolution at the level of the choriocapillaris.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.