Evidence map›Paper›PMID 28982978›Full record

ArticleThe Journal of biological chemistry2017

Defining the interaction of the protease CpaA with its type II secretion chaperone CpaB and its contribution to virulence in

Rachel L Kinsella, Juvenal Lopez, Lauren D Palmer, Nichole D Salinas, Eric P Skaar, Niraj H Tolia, Mario F Feldman

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Changes in Susceptibility Profiles ofJournal of clinical medicine · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Carbapenem-resistantiScience · 2024
    Review
  8. Review
  9. Review
  10. Uncovering the Secretion Systems ofAntibiotics (Basel, Switzerland) · 2023
    Review
  11. Article
  12. Article
  13. DNA and cell biology · 2022
    Review
  14. Article
  15. Article
  16. The Role of Antibiotic ResistantAntibiotics (Basel, Switzerland) · 2021
    Review
  17. Evolution ofInfection and drug resistance · 2021
    Article
  18. Article
  19. Article
  20. Multidrug ResistantFrontiers in microbiology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Rachel L KinsellaFrom the Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri 63110.
Juvenal LopezFrom the Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri 63110.
Lauren D Palmerthe Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee 37232.
Nichole D SalinasFrom the Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri 63110.
Eric P Skaarthe Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee 37232.
Niraj H ToliaFrom the Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri 63110.
Mario F FeldmanFrom the Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri 63110, mariofeldman@wustl.edu.ORCID 0000-0003-4497-0976
Washington University in St. Louis · USVanderbilt University Medical Center · USUniversity of Alberta · CA

Funding

Translational Analysis CoreP30DK058404 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 2002 to 2026
$29.9M
Host-mediated zinc sequestration during Acinetobacter baumannii infectionR01AI101171 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI WALTER J. CHAZIN, DAVID P. GIEDROC · 2013 to 2026
$8.2M
MOLECULAR BIOPHYSICS TRAINING PROGRAM AT VANDERBILTT32GM008320 · NIGMS · VANDERBILT UNIVERSITY · PI CHAZIN, WALTER J. · 1989 to 2023
$7.9M
Interdisciplinary Training Program in Lung ResearchT32HL094296 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Ray Stokes Peebles · 2008 to 2026
$6.3M
Defining the molecular link between zinc deficiency and pneumoniaF32AI122516 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI PALMER, LAUREN DISTERHOFT · 2016 to 2017
$113k
NHLBI NIH HHS T32 HL094296NIAID NIH HHS F32 AI122516NIAID NIH HHS R01 AI101171NIDDK NIH HHS P30 DK058404NIGMS NIH HHS T32 GM008320
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AcinetobacterAnimalsFactor VLarvaMiceMice, Inbred C57BLMolecular ChaperonesPeptide HydrolasesProtein BindingProteolysisSpleenVirulenceFactor VMolecular ChaperonesPeptide Hydrolasesbacterial pathogenesisbacterial toxinchaperonemetalloproteasetype II secretion system (T2SS)

Identifiers

PMID28982978
PMCPMC5712607
OpenAlexW2761987215

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.