SynthesisAJNR. American journal of neuroradiology2017
Endovascular Treatment of Vein of Galen Malformations: A Systematic Review and Meta-Analysis.
Synthesis in AJNR. American journal of neuroradiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Vein of Galen Aneurysmal Malformations: Updates on Technical Aspects and Functional Outcomes Post-Endovascular Treatment-A Systematic Review and Meta-Analysis.Medicina (Kaunas, Lithuania) · 2024Pooled it
- Targeted neonatal echocardiography-guided management of high flow cerebral vascular malformations: Impact of a multidisciplinary neurohemodynamics team.Journal of perinatology : official journal of the California Perinatal Association · 2026Article
- The Aortic Flow Reversal Ratio: A Quantitative Adjunct to the Bicêtre Score in Vein of Galen Malformation.Journal of clinical medicine · 2026Article
- Neuro-interventional Radiology in Paediatric Patients: An Update.Cardiovascular and interventional radiology · 2025Review
- Effective endovascular treatment of veins of Galen malformation in a child: A case study.Radiology case reports · 2025Article
- Clinical outcomes and quality of life after endovascular embolization for vein of Galen aneurysmal malformation (VGAM): a study from a low-and middle-income country.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025Article
- Vein of Galen aneurysmal malformations: retrospective evaluation of endovascular treatment outcomes.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025Article
- Ultrasound Super-Resolution Imaging of Neonatal Cerebral Vascular Reorganization.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Cerebrovascular Anomalies in the Fetus.AJNR. American journal of neuroradiology · 2025Review
- Transvenous embolization of vein of galen aneurysmal malformations with coils as a final procedure for cure: A single-institution experience of 18 years.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2024Article
- Vein of Galen aneurysmal malformation: does size affect outcome?Neuroradiology · 2024Article
- Article
- Mutation of key signaling regulators of cerebrovascular development in vein of Galen malformations.Nature communications · 2023Article
- Use of levosimendan in hemodynamic management of heart failure in two neonates with intracranial arteriovenous shunts: a case series.Italian journal of pediatrics · 2023Article
- Long-Term Outcomes of Endovascular Embolization in a Vein of Galen Aneurysmal Malformation: A Single-Center Experience.Diagnostics (Basel, Switzerland) · 2023Article
- The Use of Contrast-Enhanced Ultrasound (CEUS) in the Evaluation of the Neonatal Brain.Children (Basel, Switzerland) · 2023Review
- Heart Failure Following Sinus Venosus Defect Closure in a Patient With Vein of Galen Malformation.JACC. Case reports · 2023Article
- The composition of landmark vein of Galen malformation research: the emergence of endovascular treatments.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2023Review
- Neurodevelopmental and genetic findings in neonates with intracranial arteriovenous shunts: A case series.Frontiers in pediatrics · 2023Article
- Rapid ventricular overdrive pacing and other advanced flow-control techniques for the endovascular embolization of vein of galen malformations.Frontiers in pediatrics · 2023Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOutcomes after endovascular embolization of vein of Galen malformations remain relatively poorly described. PURPOSE: We performed a systematic review of the literature to determine outcomes and predictors of good outcomes following endovascular treatment of vein of Galen malformations. DATA SOURCES: We used Ovid MEDLINE, Ovid Embase, and the Web of Science. STUDY SELECTION: Our study consisted of all case series with ≥4 patients receiving endovascular treatment of vein of Galen malformations published through January 2017. DATA ANALYSIS: We studied the following outcomes: complete/near-complete occlusion rates, technical complications, perioperative stroke, perioperative hemorrhage, technical mortality, all-cause mortality, poor neurologic outcomes, and good neurologic outcomes. Outcomes were stratified by age-group (neonate, infant, child). A random-effects meta-analysis was performed. DATA SYNTHESIS: A total of 27 series with 578 patients were included; 41.9% of patients were neonates, 45.0% of patients were infants, and 13.1% of patients were children. All-cause mortality was 14.0% (95% CI, 8.0%-22.0%). Overall good neurologic outcome rates were 62.0% (95% CI, 57.0%-67.0%). Overall poor neurologic outcome rates were 21.0% (95% CI, 17.0%-26.0%). Neonates were significantly less likely to have good neurologic outcomes than infants (48.0%; 95% CI, 35.0%-62.0% versus 77.0%; 95% CI, 70.0%-84.0%; LIMITATIONS: Limitations were selection and publication biases.
conclusionsPatients receiving endovascular embolization of vein of Galen malformations experienced good long-term clinical outcomes in >60% of cases. Appropriate patient selection is key as treatment guided by the Bicêtre neonatal evaluation score was associated with improved neurologic outcomes.
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