Evidence map›Paper›PMID 28982705›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2017

SK Channels Regulate Resting Properties and Signaling Reliability of a Developing Fast-Spiking Neuron.

Yihui Zhang, Hai Huang

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 22 citations in OpenAlex.

  1. Input-Specific Organization of Intrinsic Excitability Expands Coding Capacity of Fast-Spiking Auditory Neurons.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  2. Article
  3. KAmerican journal of physiology. Gastrointestinal and liver physiology · 2023
    Article
  4. Vascular mechanotransduction.Physiological reviews · 2023
    Review
  5. KCNQ Channels Enable Reliable Presynaptic Spiking and Synaptic Transmission at High Frequency.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022
    Article
  6. IInternational journal of molecular sciences · 2021
    Article
  7. Mechanisms Underlying Enhancement of Spontaneous Glutamate Release by Group I mGluRs at a Central Auditory Synapse.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020
    Article
  8. Activity and Cytosolic NaThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2020
    Article
  9. Spike Activity Regulates Vesicle Filling at a Glutamatergic Synapse.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020
    Article
  10. Voltage-Independent SK-Channel Dysfunction Causes Neuronal Hyperexcitability in the Hippocampus ofThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Yihui ZhangDepartment of Cell and Molecular Biology and.
Hai HuangDepartment of Cell and Molecular Biology and hhuang5@tulane.edu.ORCID 0000-0002-6928-3198
Institute of Molecular and Cell Biology · RUTulane University · US

Funding

Synaptic mechanisms of auditory information processingR01DC016324 · NIDCD · TULANE UNIVERSITY OF LOUISIANA · PI Hai Huang · 2018 to 2026
$2.5M
Ion channels and presynaptic function of an auditory synapseR00DC012063 · NIDCD · TULANE UNIVERSITY OF LOUISIANA · PI HUANG, HAI · 2014 to 2016
$745k
Ion channels and presynaptic function of an auditory synapseK99DC012063 · NIDCD · OREGON HEALTH & SCIENCE UNIVERSITY · PI HUANG, HAI · 2012 to 2013
$177k
NIDCD NIH HHS K99 DC012063NIDCD NIH HHS R00 DC012063NIDCD NIH HHS R01 DC016324
6 · The paper itself

Abstract

Reliable and precise signal transmission is essential in circuits of the auditory brainstem to encode timing with submillisecond accuracy. Globular bushy cells reliably and faithfully transfer spike signals to the principal neurons of the medial nucleus of the trapezoid body (MNTB) through the giant glutamatergic synapse, the calyx of Held. Thus, the MNTB works as a relay nucleus that preserves the temporal pattern of firing at high frequency. Using whole-cell patch-clamp recordings, we observed a K

Indexed as

Action PotentialsAnimalsApaminBrain StemExcitatory Postsynaptic PotentialsFemaleMaleMembrane PotentialsNeuronsOrgan Culture TechniquesRatsRats, WistarShaker Superfamily of Potassium ChannelsSmall-Conductance Calcium-Activated Potassium ChannelsTime FactorsTrapezoid BodyApaminShaker Superfamily of Potassium ChannelsSmall-Conductance Calcium-Activated Potassium ChannelsexcitabilityMNTBpotassium channelresting membrane potentialSK channeltransmission fidelity

Identifiers

PMID28982705
PMCPMC5666590
OpenAlexW2764175986

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.