Evidence map›Paper›PMID 28982686›Full record

ArticleDevelopment (Cambridge, England)2017

Regulation of mitosis-meiosis transition by the ubiquitin ligase β-TrCP in male germ cells.

Tadashi Nakagawa, Teng Zhang, Ryo Kushi, Seiji Nakano, Takahiro Endo, Makiko Nakagawa, Noriko Yanagihara, David Zarkower, Keiko Nakayama

Open access · bronzeAbstract read
In one paragraph

Article in Development (Cambridge, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Tadashi NakagawaDivision of Cell Proliferation, ART, Tohoku University Graduate School of Medicine, Sendai, Miyagi 980-8575, Japan.
Teng ZhangDepartment of Genetics, Cell Biology, and Development, and Developmental Biology Center, University of Minnesota, Minneapolis, MN 55455, USA.
Ryo KushiDivision of Cell Proliferation, ART, Tohoku University Graduate School of Medicine, Sendai, Miyagi 980-8575, Japan.
Seiji NakanoDivision of Cell Proliferation, ART, Tohoku University Graduate School of Medicine, Sendai, Miyagi 980-8575, Japan.
Takahiro EndoDivision of Cell Proliferation, ART, Tohoku University Graduate School of Medicine, Sendai, Miyagi 980-8575, Japan.
Makiko NakagawaDivision of Cell Proliferation, ART, Tohoku University Graduate School of Medicine, Sendai, Miyagi 980-8575, Japan.
Noriko YanagiharaDivision of Cell Proliferation, ART, Tohoku University Graduate School of Medicine, Sendai, Miyagi 980-8575, Japan.ORCID 0000-0002-4840-2274
David ZarkowerDepartment of Genetics, Cell Biology, and Development, and Developmental Biology Center, University of Minnesota, Minneapolis, MN 55455, USA.
Keiko NakayamaDivision of Cell Proliferation, ART, Tohoku University Graduate School of Medicine, Sendai, Miyagi 980-8575, Japan nakayak2@med.tohoku.ac.jp.ORCID 0000-0003-0134-6401
Tohoku University · JPUniversity of Minnesota · US

Funding

DMRT1 IN MAMMALIAN SEXUAL DEVELOPMENTR01GM059152 · NIGMS · UNIVERSITY OF MINNESOTA TWIN CITIES · PI BARDWELL, VIVIAN J, ZARKOWER, DAVID A. · 1999 to 2019
$8.8M
Stem Cell Biology Training ProgramT32GM113846 · NIGMS · UNIVERSITY OF MINNESOTA · PI PERLINGEIRO, RITA C. R. · 2015 to 2019
$712k
NIGMS NIH HHS R01 GM059152NIGMS NIH HHS T32 GM113846
6 · The paper itself

Abstract

The mitosis-meiosis transition is essential for spermatogenesis. Specific and timely downregulation of the transcription factor DMRT1, and consequent induction of

Indexed as

MeiosisMitosisAdaptor Proteins, Signal TransducingAmino Acid SequenceAnimalsApoptosisbeta-Transducin Repeat-Containing ProteinsFertilityGene DeletionGene TargetingHeterozygoteMaleMice, Inbred C57BLMice, KnockoutProtein BindingProtein Processing, Post-TranslationalAdaptor Proteins, Signal Transducingbeta-Transducin Repeat-Containing ProteinsDMRT1 proteinStra8 protein, mouseTranscription FactorsUbiquitinDmrt1MeiosisMitosisSpermatogenesisUbiquitin ligaseUbiquitin-proteasome systemβ-TrCP1 (BTRC)β-TrCP2 (Fbxw11)

Identifiers

PMID28982686
PMCPMC5719248
OpenAlexW2763114465

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.