Evidence map›Paper›PMID 28982681›Full record

ArticleDisease models & mechanisms2017

Early neonatal loss of inhibitory synaptic input to the spinal motor neurons confers spina bifida-like leg dysfunction in a chicken model.

Md Sakirul Islam Khan, Hiroaki Nabeka, Farzana Islam, Tetsuya Shimokawa, Shouichiro Saito, Xuan Li, Soichiro Kawabe, Fumihiko Hamada, Tetsuya Tachibana, Seiji Matsuda

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Disease models & mechanisms, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. State of the art in translating experimental myelomeningocele research to the bedside.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Md Sakirul Islam KhanDepartment of Anatomy and Embryology, Graduate School of Medicine, Ehime University, Toon 791-0295, Ehime, Japan sakirul@m.ehime-u.ac.jp sakirul.khan@gmail.com.ORCID 0000-0001-5734-0899
Hiroaki NabekaDepartment of Anatomy and Embryology, Graduate School of Medicine, Ehime University, Toon 791-0295, Ehime, Japan.
Farzana IslamDepartment of Anatomy and Embryology, Graduate School of Medicine, Ehime University, Toon 791-0295, Ehime, Japan.
Tetsuya ShimokawaDepartment of Anatomy and Embryology, Graduate School of Medicine, Ehime University, Toon 791-0295, Ehime, Japan.
Shouichiro SaitoLaboratory of Veterinary Anatomy, Faculty of Applied Biological Sciences, Gifu University, Yanagido, Gifu 501-1128, Japan.
Xuan LiDepartment of Anatomy and Embryology, Graduate School of Medicine, Ehime University, Toon 791-0295, Ehime, Japan.
Soichiro KawabeFukui Prefectural Dinosaur Museum, Katsuyama, Fukui 911-8601, Japan.
Fumihiko HamadaDepartment of Human Anatomy, Faculty of Medicine, Oita University, Yufu, Oita 879-5593, Japan.
Tetsuya TachibanaDepartment of Agrobiological Science, Faculty of Agriculture, Ehime University, Matsuyama 790-8566, Japan.
Seiji MatsudaDepartment of Anatomy and Embryology, Graduate School of Medicine, Ehime University, Toon 791-0295, Ehime, Japan.
Ehime University · JPBangladesh Agricultural University · BDFukui Prefectural Dinosaur Museum · JPGifu University · JPOita University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spina bifida aperta (SBA), one of the most common congenital malformations, causes lifelong neurological complications, particularly in terms of motor dysfunction. Fetuses with SBA exhibit voluntary leg movements

Indexed as

AnimalsAnimals, NewbornApoptosisBehavior, AnimalCaspase 3Chick EmbryoChickensCholineDisease Models, AnimalExtremitiesgamma-Aminobutyric AcidInterneuronsLumbar VertebraeMotor NeuronsNerve DegenerationSpinal CordCaspase 3Cholinegamma-Aminobutyric AcidChicken modelGABAergic transmissionMotor dysfunctionNeural tube defectNeurodegenerationSynaptic inputs

Identifiers

PMID28982681
PMCPMC5769610
OpenAlexW2761980354

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.