Evidence map›Paper›PMID 28982576›Full record

ArticleThe Journal of allergy and clinical immunology2018

Asthma predisposition and respiratory syncytial virus infection modulate transient receptor potential vanilloid 1 function in children's airways.

Terri J Harford, Fariba Rezaee, Rachel G Scheraga, Mitchell A Olman, Giovanni Piedimonte

Abstract readLetter
In one paragraph

Article in The Journal of allergy and clinical immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Update on the Role of β2AR and TRPV1 in Respiratory Diseases.International journal of molecular sciences · 2024
    Review
  5. Cytokines reprogram airway sensory neurons in asthma.bioRxiv : the preprint server for biology · 2024
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. RSV infection potentiates TRPVAmerican journal of physiology. Lung cellular and molecular physiology · 2021
    Article
  11. Review
  12. Article
  13. Review
  14. Disruption of the airway epithelial barrier in a murine model of respiratory syncytial virus infection.American journal of physiology. Lung cellular and molecular physiology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Terri J HarfordCenter for Pediatric Research, Pediatric Institute and Children's Hospital, The Cleveland Clinic, Cleveland, Ohio.
Fariba RezaeeCenter for Pediatric Research, Pediatric Institute and Children's Hospital, The Cleveland Clinic, Cleveland, Ohio.
Rachel G ScheragaDepartment of Pathobiology, Lerner Research Institute, The Cleveland Clinic, Cleveland, Ohio.
Mitchell A OlmanDepartment of Pathobiology, Lerner Research Institute, The Cleveland Clinic, Cleveland, Ohio.
Giovanni PiedimonteCenter for Pediatric Research, Pediatric Institute and Children's Hospital, The Cleveland Clinic, Cleveland, Ohio. Electronic address: PIEDIMG@ccf.org.

Funding

NEUROGENIC INFLAMMATORY RESPONSE TO RSVR01HL061007 · NHLBI · WEST VIRGINIA UNIVERSITY · PI PIEDIMONTE, GIOVANNI · 1999 to 2022
$7.2M
TRPV4-PI3K Axis Mediates Pulmonary and Cardiac FibrosisR01HL133721 · NHLBI · CLEVELAND CLINIC LERNER COM-CWRU · PI OLMAN, MITCHELL ALAN, PRASAD, SATHYAMANGLA V · 2017 to 2020
$2.2M
Myofibroblast differentiation and fibrosis are mediated by TRPV4 mechanosensingR01HL119792 · NHLBI · CLEVELAND CLINIC LERNER COM-CWRU · PI OLMAN, MITCHELL ALAN · 2014 to 2017
$1.6M
Transient Receptor Potential Vanilloid 4 (TRPV4) mediates the host defense and lung injury response to bacterial pneumoniaK08HL133380 · NHLBI · CLEVELAND CLINIC LERNER COM-CWRU · PI SCHERAGA, RACHEL GREENBERG · 2016 to 2020
$809k
Airway Epithelial Barrier Dysfunction In Response to Respiratory Syncytial VirusK08AI112781 · NIAID · UNIVERSITY OF ROCHESTER · PI REZAEE, FARIBA · 2015 to 2018
$734k
NHLBI NIH HHS K08 HL133380NHLBI NIH HHS R01 HL061007NHLBI NIH HHS R01 HL119792NHLBI NIH HHS R01 HL133721NIAID NIH HHS K08 AI112781
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultAge FactorsAsthmaCalciumChildHumansRespiratory Syncytial VirusesRespiratory Syncytial Virus InfectionsTRPV Cation ChannelsCalciumTRPV1 receptorTRPV Cation Channels

Identifiers

PMID28982576
PMCPMC5758408

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.