Evidence map›Paper›PMID 28982267›Full record

ReviewPharmacogenomics2017

Institutional profile: translational pharmacogenomics at the Icahn School of Medicine at Mount Sinai.

Stuart A Scott, Aniwaa Owusu Obeng, Mariana R Botton, Yao Yang, Erick R Scott, Stephen B Ellis, Richard Wallsten, Tom Kaszemacher, Xiang Zhou, Rong Chen and 18 more

Abstract readReview
In one paragraph

Review in Pharmacogenomics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Advancing Pharmacogenomics from Single-Gene to Preemptive Testing.Annual review of genomics and human genetics · 2022
    Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Gene-Based Analysis Reveals Sex-Specific Genetic Risk Factors of COPD.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2021
    Article
  9. Article
  10. Trait Insights Gained by Comparing Genome-Wide Association Study Results using Different Chronic Obstructive Pulmonary Disease Definitions.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2020
    Article
  11. Pharmacy students' attitudes and perceptions toward pharmacogenomics education.American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists · 2019
    Article
  12. Review
  13. Article
  14. Pharmacogenomic Approaches for Automated Medication Risk Assessment in People with Polypharmacy.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors.

Stuart A ScottDepartment of Genetics & Genomic Sciences, Icahn School of Medicine at Mount Sinai, NY 10029, USA.
Aniwaa Owusu ObengThe Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, NY 10029, USA.
Mariana R BottonDepartment of Genetics & Genomic Sciences, Icahn School of Medicine at Mount Sinai, NY 10029, USA.
Yao YangDepartment of Genetics & Genomic Sciences, Icahn School of Medicine at Mount Sinai, NY 10029, USA.
Erick R ScottDepartment of Genetics & Genomic Sciences, Icahn School of Medicine at Mount Sinai, NY 10029, USA.
Stephen B EllisThe Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, NY 10029, USA.
Richard WallstenSema4, a Mount Sinai venture, Stamford, CT 06902, USA.
Tom KaszemacherThe Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, NY 10029, USA.
Xiang ZhouDepartment of Genetics & Genomic Sciences, Icahn School of Medicine at Mount Sinai, NY 10029, USA.
Rong ChenDepartment of Genetics & Genomic Sciences, Icahn School of Medicine at Mount Sinai, NY 10029, USA.
Paola NicolettiDepartment of Genetics & Genomic Sciences, Icahn School of Medicine at Mount Sinai, NY 10029, USA.
Hetanshi NaikDepartment of Genetics & Genomic Sciences, Icahn School of Medicine at Mount Sinai, NY 10029, USA.
Eimear E KennyDepartment of Genetics & Genomic Sciences, Icahn School of Medicine at Mount Sinai, NY 10029, USA.
Aida VegaMount Sinai Faculty Practice Associates Primary Care Program, Icahn School of Medicine at Mount Sinai, NY 10029, USA.
Eva WaiteMount Sinai Faculty Practice Associates Primary Care Program, Icahn School of Medicine at Mount Sinai, NY 10029, USA.
George A DiazDepartment of Genetics & Genomic Sciences, Icahn School of Medicine at Mount Sinai, NY 10029, USA.
Joel DudleyDepartment of Genetics & Genomic Sciences, Icahn School of Medicine at Mount Sinai, NY 10029, USA.
Jonathan L HalperinThe Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, NY 10029, USA.
Lisa EdelmannDepartment of Genetics & Genomic Sciences, Icahn School of Medicine at Mount Sinai, NY 10029, USA.
Andrew KasarskisDepartment of Genetics & Genomic Sciences, Icahn School of Medicine at Mount Sinai, NY 10029, USA.
Jean-Sébastien HulotCardiovascular Research Center, Icahn School of Medicine at Mount Sinai, NY 10029, USA.
Inga PeterDepartment of Genetics & Genomic Sciences, Icahn School of Medicine at Mount Sinai, NY 10029, USA.
Erwin P BottingerThe Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, NY 10029, USA.
Kurt HirschhornDepartment of Genetics & Genomic Sciences, Icahn School of Medicine at Mount Sinai, NY 10029, USA.
Pamela SklarDepartment of Genetics & Genomic Sciences, Icahn School of Medicine at Mount Sinai, NY 10029, USA.
Judy H ChoDepartment of Genetics & Genomic Sciences, Icahn School of Medicine at Mount Sinai, NY 10029, USA.
Robert J DesnickDepartment of Genetics & Genomic Sciences, Icahn School of Medicine at Mount Sinai, NY 10029, USA.
Eric E SchadtDepartment of Genetics & Genomic Sciences, Icahn School of Medicine at Mount Sinai, NY 10029, USA.

Funding

The Electronic Medical Records and Genomics (eMERGE) Network Phase III Coordinating Center (U01)U01HG008701 · NHGRI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI PETERSON, JOSEPH F. · 2015 to 2019
$7.1M
Genomic Medicine Pilot For Hypertension And Kidney Disease In Primary CareU01HG007278 · NHGRI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI HOROWITZ, CAROL R · 2013 to 2018
$5.7M
Biorepository for Genomic Medicine in diverse CommunitiesU01HG006380 · NHGRI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI BOTTINGER, ERWIN P. · 2011 to 2015
$4.5M
Transforming Genomics with 5 PB Big Omics Data Engine Cray CS300-AC SupercomputerS10OD018522 · OD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KOVATCH, PATRICIA · 2014 to 2014
$1.9M
The Pharmacogenomic Control of Clopidogrel Response in Acute Coronary SyndromesK23GM104401 · NIGMS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI SCOTT, STUART ALEXANDER · 2013 to 2016
$778k
NHGRI NIH HHS U01 HG006380NHGRI NIH HHS U01 HG007278NHGRI NIH HHS U01 HG008701NIGMS NIH HHS K23 GM104401NIH HHS S10 OD018522
6 · The paper itself

Abstract

For almost 50 years, the Icahn School of Medicine at Mount Sinai has continually invested in genetics and genomics, facilitating a healthy ecosystem that provides widespread support for the ongoing programs in translational pharmacogenomics. These programs can be broadly cataloged into discovery, education, clinical implementation and testing, which are collaboratively accomplished by multiple departments, institutes, laboratories, companies and colleagues. Focus areas have included drug response association studies and allele discovery, multiethnic pharmacogenomics, personalized genotyping and survey-based education programs, pre-emptive clinical testing implementation and novel assay development. This overview summarizes the current state of translational pharmacogenomics at Mount Sinai, including a future outlook on the forthcoming expansions in overall support, research and clinical programs, genomic technology infrastructure and the participating faculty.

Indexed as

AllelesGenomeGenomicsHumansPharmacogeneticsPrecision MedicineSchools, MedicalTranslational Research, Biomedicalclinical implementationdiscoveryeducationgenetic testingIcahn School of Medicine at Mount Sinaipharmacogeneticspharmacogenomics

Identifiers

PMID28982267
PMCPMC5694020

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.