Evidence map›Paper›PMID 28982135›Full record

ArticlePloS one2017

Changes in aortic pulse wave velocity of four thoracic aortic stent grafts in an ex vivo porcine model.

Hector W L de Beaufort, Margherita Coda, Michele Conti, Theodorus M J van Bakel, Foeke J H Nauta, Ettore Lanzarone, Frans L Moll, Joost A van Herwaarden, Ferdinando Auricchio, Santi Trimarchi

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 60 citations in OpenAlex.

  1. Review
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  10. A structural approach to 3D-printing arterial phantoms with physiologically comparable mechanical characteristics: Preliminary observations.Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine · 2022
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  11. Article
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  13. Arterial Stiffness in Aortic Stenosis.Arquivos brasileiros de cardiologia · 2021
    Article
  14. Article
  15. Article
  16. Cardiac remodelling following thoracic endovascular aortic repair for descending aortic aneurysms.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2019
    Article
  17. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Hector W L de BeaufortThoracic Aortic Research Center, Policlinico San Donato IRCCS, University of Milan, San Donato Milanese, Italy.ORCID http://orcid.org/0000-0003-1658-9692
Margherita CodaDepartment of Civil Engineering and Architecture, University of Pavia, Pavia, Italy.
Michele ContiDepartment of Civil Engineering and Architecture, University of Pavia, Pavia, Italy.
Theodorus M J van BakelThoracic Aortic Research Center, Policlinico San Donato IRCCS, University of Milan, San Donato Milanese, Italy.
Foeke J H NautaThoracic Aortic Research Center, Policlinico San Donato IRCCS, University of Milan, San Donato Milanese, Italy.
Ettore LanzaroneInstitute of Applied Mathematics and Information Technologies (IMATI), National Research Council of Italy (CNR), Milan, Italy.
Frans L MollDepartment of Vascular Surgery, University Medical Center Utrecht, Utrecht, the Netherlands.
Joost A van HerwaardenDepartment of Vascular Surgery, University Medical Center Utrecht, Utrecht, the Netherlands.
Ferdinando AuricchioDepartment of Civil Engineering and Architecture, University of Pavia, Pavia, Italy.
Santi TrimarchiThoracic Aortic Research Center, Policlinico San Donato IRCCS, University of Milan, San Donato Milanese, Italy.
University of Milan · ITUniversity of Pavia · ITUniversity Medical Center Utrecht · NLIstituto di Matematica Applicata e Tecnologie Informatiche · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThoracic endovascular aortic repair (TEVAR) has been shown to lead to increased aortic stiffness. The aim of this study was to investigate the effect of stent graft type and stent graft length on aortic stiffness in a controlled, experimental setting.

methodsTwenty porcine thoracic aortas were connected to a pulsatile mock loop system. Intraluminal pressure was recorded at two sites in order to measure pulse wave velocity (PWV) for each aorta: before stent graft deployment (t1); after deployment of a 100-mm long stent graft (t2); and after distal extension through deployment of a second 100-mm long stent graft (t3). Four different types of stent grafts (Conformable Gore® TAG® Device, Bolton Relay® Device, Cook Zenith Alpha™, and Medtronic Valiant®) were evaluated.

resultsFor the total cohort of 20 aortas, PWV increased by a mean 0.6 m/s or 8.9% of baseline PWV after deployment of a 100-mm proximal stent graft (P<0.001), and by a mean 1.4 m/s or 23.0% of baseline PWV after distal extension of the stent graft (P<0.001). Univariable regression analysis showed a significant correlation between aortic PWV and extent of stent graft coverage, (P<0.001), but no significant effect of baseline aortic length, baseline aortic PWV, or stent graft type on the percentual increase in PWV at t2 or at t3.

conclusionsIn this experimental set-up, aortic stiffness increased significantly after stent graft deployment with each of the four types of stent graft, with the increase in aortic stiffness depending on the extent of stent graft coverage.

Indexed as

Models, AnimalStentsAnimalsAorta, ThoracicIn Vitro TechniquesSwine

Identifiers

PMID28982135
PMCPMC5642022
OpenAlexW2763381053

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.