ArticleNucleic acids research2018
The Encyclopedia of Proteome Dynamics: a big data ecosystem for (prote)omics.
Article in Nucleic acids research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
13 citing papers in PubMed.
- POT-3 preferentially binds the terminal DNA-repeat on the telomeric G-overhang.Nucleic acids research · 2023Article
- Novel biochemical, structural, and systems insights into inflammatory signaling revealed by contextual interaction proteomics.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Computational analysis of cortical neuronal excitotoxicity in a large animal model of neonatal brain injury.Journal of neurodevelopmental disorders · 2022Article
- iProX in 2021: connecting proteomics data sharing with big data.Nucleic acids research · 2022Article
- The exon-junction complex helicase eIF4A3 controls cell fate via coordinated regulation of ribosome biogenesis and translational output.Science advances · 2021Article
- Erosion of human X chromosome inactivation causes major remodeling of the iPSC proteome.Cell reports · 2021Article
- Lentiviral mediated RPE65 gene transfer in healthy hiPSCs-derived retinal pigment epithelial cells markedly increased RPE65 mRNA, but modestly protein level.Scientific reports · 2020Article
- A mechanistic integrative computational model of macrophage polarization: Implications in human pathophysiology.PLoS computational biology · 2019Article
- Quantitative analysis of T cell proteomes and environmental sensors during T cell differentiation.Nature immunology · 2019Article
- The Encyclopedia of Proteome Dynamics: the KinoViewer.Bioinformatics (Oxford, England) · 2019Article
- The 2018 Nucleic Acids Research database issue and the online molecular biology database collection.Nucleic acids research · 2018Article
- Proteome-wide analysis of protein abundance and turnover remodelling during oncogenic transformation of human breast epithelial cells.Wellcome open research · 2018Article
- Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Driven by improvements in speed and resolution of mass spectrometers (MS), the field of proteomics, which involves the large-scale detection and analysis of proteins in cells, tissues and organisms, continues to expand in scale and complexity. There is a resulting growth in datasets of both raw MS files and processed peptide and protein identifications. MS-based proteomics technology is also used increasingly to measure additional protein properties affecting cellular function and disease mechanisms, including post-translational modifications, protein-protein interactions, subcellular and tissue distributions. Consequently, biologists and clinicians need innovative tools to conveniently analyse, visualize and explore such large, complex proteomics data and to integrate it with genomics and other related large-scale datasets. We have created the Encyclopedia of Proteome Dynamics (EPD) to meet this need (https://peptracker.com/epd/). The EPD combines a polyglot persistent database and web-application that provides open access to integrated proteomics data for >30 000 proteins from published studies on human cells and model organisms. It is designed to provide a user-friendly interface, featuring graphical navigation with interactive visualizations that facilitate powerful data exploration in an intuitive manner. The EPD offers a flexible and scalable ecosystem to integrate proteomics data with genomics information, RNA expression and other related, large-scale datasets.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.