Evidence map›Paper›PMID 28981577›Full record

ArticleBriefings in bioinformatics2019

'Multi-omic' data analysis using O-miner.

Ajanthah Sangaralingam, Abu Z Dayem Ullah, Jacek Marzec, Emanuela Gadaleta, Ai Nagano, Helen Ross-Adams, Jun Wang, Nicholas R Lemoine, Claude Chelala

Abstract read
In one paragraph

Article in Briefings in bioinformatics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Wheat Omics: Advancements and Opportunities.Plants (Basel, Switzerland) · 2023
    Review
  6. Review
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ajanthah SangaralingamBarts Cancer Institute, Queen Mary University of London.
Abu Z Dayem UllahBarts Cancer Institute, Queen Mary University of London.
Jacek MarzecBarts Cancer Institute, Queen Mary University of London.
Emanuela GadaletaBarts Cancer Institute, Queen Mary University of London.
Ai NaganoBarts Cancer Institute, Queen Mary University of London.
Helen Ross-AdamsBarts Cancer Institute, Queen Mary University of London.
Jun WangBarts Cancer Institute, Queen Mary University of London.
Nicholas R LemoineBarts Cancer Institute, Queen Mary University of London.
Claude ChelalaBarts Cancer Institute, co-Lead of the Computational Biology Centre at the Life Science Initiative, Queen Mary University of London.

Funding

Cancer Research UK 12008
6 · The paper itself

Abstract

Innovations in -omics technologies have driven advances in biomedical research. However, integrating and analysing the large volumes of data generated from different high-throughput -omics technologies remain a significant challenge to basic and clinical scientists without bioinformatics skills or access to bioinformatics support. To address this demand, we have significantly updated our previous O-miner analytical suite, to incorporate several new features and data types to provide an efficient and easy-to-use Web tool for the automated analysis of data from '-omics' technologies. Created from a biologist's perspective, this tool allows for the automated analysis of large and complex transcriptomic, genomic and methylomic data sets, together with biological/clinical information, to identify significantly altered pathways and prioritize novel biomarkers/targets for biological validation. Our resource can be used to analyse both in-house data and the huge amount of publicly available information from array and sequencing platforms. Multiple data sets can be easily combined, allowing for meta-analyses. Here, we describe the analytical pipelines currently available in O-miner and present examples of use to demonstrate its utility and relevance in maximizing research output. O-miner Web server is free to use and is available at http://www.o-miner.org.

Indexed as

Data AnalysisSoftwareComputational BiologyDatabases, GeneticDNA MethylationGene DosageGene Expression ProfilingGenomicsHumansInternetNeoplasmsSequence Analysis, RNASoftware DesignWhole Genome Sequencing

Identifiers

PMID28981577
PMCPMC6357557

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.