Evidence map›Paper›PMID 28981379›Full record

Trial reportJournal of women's health (2002)2018

A Pilot Randomized Controlled Trial of a Computer-Delivered Brief Intervention for Substance Use and Risky Sex During Pregnancy.

Golfo Tzilos Wernette, Melissa Plegue, Christopher W Kahler, Ananda Sen, Caron Zlotnick

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of women's health (2002), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 10 pooled it
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 10 syntheses or guidelines pooled it, 47 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Digital Help for Substance Users (SU): A Systematic Review.International journal of environmental research and public health · 2022
    Pooled it
  5. Pooled it
  6. eHealth Interventions to Treat Substance Use in Pregnancy: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2021
    Pooled it
  7. Complex solutions for a complex problem: A meta-analysis of the efficacy of multiple-behavior interventions on change in outcomes related to HIV.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2021
    Pooled it
  8. More behavioral recommendations produce more change: A meta-analysis of efficacy of multibehavior recommendations to reduce nonmedical substance use.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2020
    Pooled it
  9. Pooled it
  10. Pooled it
  11. Trial
  12. Trial
  13. Trial
  14. Article
  15. Review
  16. Cannabis and Pregnancy: A Review.Obstetrical & gynecological survey · 2023
    Review
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Golfo Tzilos Wernette1 Department of Family Medicine, University of Michigan , Ann Arbor, Michigan.
Melissa Plegue1 Department of Family Medicine, University of Michigan , Ann Arbor, Michigan.
Christopher W Kahler2 Center for Alcohol and Addiction Studies, Brown University School of Public Health , Providence, Rhode Island.
Ananda Sen1 Department of Family Medicine, University of Michigan , Ann Arbor, Michigan.
Caron Zlotnick3 Department of Psychiatry and Human Behavior, Brown University , Providence, Rhode Island.
University of Michigan · USJohn Brown University · USUniversity of Cape Town · ZA

Funding

Computer Intervention for HIV/STI Risk and Drug Use During PregnancyR21HD075658 · NICHD · BUTLER HOSPITAL (PROVIDENCE, RI) · PI TZILOS WERNETTE, GOLFO K, ZLOTNICK, CARON · 2013 to 2014
$406k
NICHD NIH HHS R21 HD075658
6 · The paper itself

Abstract

backgroundSexually transmitted infections (STIs) are an increasingly critical and costly health problem for American childbearing women. Pregnant women who misuse substances are more likely to engage in risky sexual behavior that leads to STIs. Substance use and risky sex during pregnancy are both associated with numerous negative consequences for the woman and the developing fetus. STUDY

designA two-group, randomized controlled trial.

participantsRecruitment of 50 pregnant women (30% Latina; 24.4 years old [SD = 5.31]) with an average of 13 weeks gestation (SD = 4.5 weeks) was conducted at a prenatal clinic in a large inner-city hospital. Recruitment took place between 2015 and 2016, and data analysis took place in 2016.

interventionA computer-delivered, single-session brief motivational intervention plus booster session addressing both substance use and STI risk.

objectiveTo assess participants' perceptions of the intervention and to examine the preliminary efficacy in reduction of substance use and risky sex at 4-month follow-up assessment.

resultsThere were consistently very high ratings of acceptability of the intervention, ranging between 6.3 and 6.8 on a 1-7 scale. At the 4-month follow-up, participants in the intervention arm reported a significantly larger reduction (54%) in any marijuana or alcohol use compared with participants in the control group (16%) (p = 0.015) based on two-group clustered logistic regression using a generalized estimating equations approach. There was a higher reduction in condomless vaginal sex at follow-up in the health checkup for expectant moms (HCEM) arm than control (27% vs. 5%), although this was not significant (p = 0.127).

conclusionsThe results of this pilot study are encouraging with respect to the acceptability and preliminary efficacy of an intervention in reducing alcohol/marijuana use and condomless sex during pregnancy, supporting the next step of testing the intervention in a larger sample.

Indexed as

Risk-TakingAdultCondomsFemaleHIV InfectionsHumansMaternal BehaviorMotivational InterviewingOutcome Assessment, Health CarePilot ProjectsPregnancyPregnancy ComplicationsPrenatal CareRisk FactorsRisk Reduction BehaviorSexual Behaviorbrief interventionpregnancyreproductive healthsexually transmitted infectionssubstance abuse

Identifiers

PMID28981379
PMCPMC5771551
OpenAlexW2761458271

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.