Evidence map›Paper›PMID 28980861›Full record

ArticleCell cycle (Georgetown, Tex.)2018

Budding yeast CENP-A

Prashant K Mishra, Kriti S Thapa, Panyue Chen, Suyu Wang, Tony R Hazbun, Munira A Basrai

Open access · bronzeAbstract read
In one paragraph

Article in Cell cycle (Georgetown, Tex.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Prashant K Mishraa Genetics Branch , National Cancer Institute , National Institutes of Health , Bethesda , MD , USA.
Kriti S Thapab Purdue University , Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University Center for Cancer Research (PUCCR) , West Lafayette , IN , USA.ORCID 0000-0003-3771-3533
Panyue Chenb Purdue University , Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University Center for Cancer Research (PUCCR) , West Lafayette , IN , USA.
Suyu Wangb Purdue University , Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University Center for Cancer Research (PUCCR) , West Lafayette , IN , USA.
Tony R Hazbunb Purdue University , Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University Center for Cancer Research (PUCCR) , West Lafayette , IN , USA.ORCID 0000-0003-0675-8093
Munira A Basraia Genetics Branch , National Cancer Institute , National Institutes of Health , Bethesda , MD , USA.
Purdue University West Lafayette · USNational Institutes of Health · US

Funding

Transgenic Mouse Core Facility Shared Resource (TMCF-SR)P30CA023168 · NCI · PURDUE UNIVERSITY WEST LAFAYETTE · PI Andrea L Kasinski · 1985 to 2026
$43.4M
Molecular Determinants of Chromosome Transmission and Cell Cycle RegulationZIABC010822 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI BASRAI, MUNIRA · 2009 to 2025
$29.2M
NCI NIH HHS P30 CA023168
6 · The paper itself

Abstract

Shugoshin is an evolutionarily conserved protein, which is involved in tension sensing on mitotic chromosomes, kinetochore biorientation, and protection of centromeric (CEN) cohesin for faithful chromosome segregation. Interaction of the C-terminus of Sgo1 with phosphorylated histone H2A regulates its association with CEN and pericentromeric (peri-CEN) chromatin, whereas mutations in histone H3 selectively compromise the association of Sgo1 with peri-CEN but not CEN chromatin. Given that histone H3 is absent from CEN and is replaced by a histone H3 variant CENP-A

Indexed as

Cell CycleCentromereChromatinChromosomal Proteins, Non-HistoneChromosome SegregationDNA-Binding ProteinsNuclear ProteinsProtein BindingProtein DomainsSaccharomyces cerevisiae ProteinsSaccharomycetalesTwo-Hybrid System TechniquesChromatinChromosomal Proteins, Non-HistoneCSE4 protein, S cerevisiaeDNA-Binding ProteinsNuclear ProteinsSaccharomyces cerevisiae ProteinsSgo1 protein, S cerevisiaecell cycleCENP-AcentromereCse4gene regulationkinetochoremitosisSgo1Shugoshinyeast

Identifiers

PMID28980861
PMCPMC5815428
OpenAlexW2763946060

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.