ArticleInsect science2019
Characterization and functional analysis of hsp18.3 gene in the red flour beetle, Tribolium castaneum.
Article in Insect science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
11 citing papers in PubMed, 39 citations in OpenAlex.
- Article
- Identification and Characterization ofInternational journal of molecular sciences · 2025Article
- TheFrontiers in molecular biosciences · 2022Article
- Article
- Research Progress on Oviposition-Related Genes in Insects.Journal of insect science (Online) · 2020Review
- A new neuropeptide insect parathyroid hormone iPTH in the red flour beetle Tribolium castaneum.PLoS genetics · 2020Article
- Identifications, Characteristics, and Expression Patterns of Small Heat Shock Protein Genes in a Major Mulberry Pest, Glyphodes pyloalis (Lepidoptera: Pyralidae).Journal of insect science (Online) · 2020Article
- Article
- Identification and Expression Analysis of Four Small Heat Shock Protein Genes in Cigarette Beetle,Insects · 2019Article
- Insect Behavior and Physiological Adaptation Mechanisms Under Starvation Stress.Frontiers in physiology · 2019Article
- Induced Thermotolerance and Expression of Three KeyFrontiers in physiology · 2019Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
Small heat shock proteins (sHSPs) are diverse and mainly function as molecular chaperones to protect organisms and cells from various stresses. In this study, hsp18.3, one Tribolium castaneum species-specific shsp, has been identified. Quantitative real-time polymerase chain reaction illustrated that Tchsp18.3 is expressed in all developmental stages, and is highly expressed at early pupal and late adult stages, while it is highly expressed in ovary and fat body at the adult period. Moreover, it was up-regulated 4532 ± 396-fold in response to enhanced heat stress but not to cold stress; meanwhile the lifespan of adults in ds-Tchsp18.3 group reduced by 15.8% from control group under starvation. Laval RNA interference (RNAi) of Tchsp18.3 caused 86.1% ± 4.5% arrested pupal eclosion and revealed that Tchsp18.3 played an important role in insect development. In addition, parental RNAi of Tchsp18.3 reduced the oviposition amount by 94.7%. These results suggest that Tchsp18.3 is not only essential for the resistance to heat and starvation stress, but also is critical for normal development and reproduction in T. castaneum.
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Registered trials
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