Evidence map›Paper›PMID 28980184›Full record

ArticleBiological trace element research2018

MRP2 and the Transport Kinetics of Cysteine Conjugates of Inorganic Mercury.

Cláudia Oliveira, Lucy Joshee, Christy C Bridges

Abstract read
In one paragraph

Article in Biological trace element research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. In vitro Transport Ability ofOncoTargets and therapy · 2020
    Article
  5. Neurodevelopmental Effects of Mercury.Advances in neurotoxicology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 2 countries.

Cláudia OliveiraDepartment of Biomedical Sciences, Mercer University School of Medicine, 1501 College St., Macon, GA, 31207, USA.
Lucy JosheeDepartment of Biomedical Sciences, Mercer University School of Medicine, 1501 College St., Macon, GA, 31207, USA.
Christy C BridgesDepartment of Biomedical Sciences, Mercer University School of Medicine, 1501 College St., Macon, GA, 31207, USA. Bridges_cc@mercer.edu.ORCID http://orcid.org/0000-0003-1603-1445
Mercer University · US

Funding

Proximal Tubular Transport of Mercury and Effects of Reduced Renal MassR15ES019991 · NIEHS · MERCER UNIVERSITY MACON · PI BRIDGES, CHRISTY C · 2011 to 2011
$471k
Foundation for the National Institutes of Health ES019991-01NIEHS NIH HHS R15 ES019991
6 · The paper itself

Abstract

Human exposure to mercuric species occurs regularly throughout the world. Mercuric ions may accumulate in target cells and subsequently lead to cellular intoxication and death. Therefore, it is important to have a thorough understanding of how transportable species of mercury are handled by specific membrane transporters. The purpose of the current study was to characterize the transport kinetics of cysteine (Cys)-S-conjugates of inorganic mercury (Cys-S-Hg-S-Cys) at the site of the multidrug resistance-associated transporter 2 (MRP2). In order to estimate the maximum velocity (V

Indexed as

AnimalsATP-Binding Cassette, Sub-Family C ProteinsBiological TransportCysteineKidneyKineticsMaleMercuryMultidrug Resistance-Associated Protein 2RatsRats, WistarABCC2 protein, humanATP-Binding Cassette, Sub-Family C ProteinsCysteineMercuryMultidrug Resistance-Associated Protein 2KidneyMercuryMultidrug resistance-associated protein 2Transport

Identifiers

PMID28980184
PMCPMC5882609
OpenAlexW2763672425

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.