Evidence map›Paper›PMID 28980021›Full record

ArticleInternational urogynecology journal2018

Comparison of strength of sacrocolpopexy mesh attachment using barbed and nonbarbed sutures.

Marjorie L Pilkinton, Gregory C Levine, Laura Bennett, Harvey A Winkler, Dara F Shalom, Peter S Finamore

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in International urogynecology journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Marjorie L PilkintonDepartment of Obstetrics and Gynecology Division of Urogynecology, Northwell Health System, 865 Northern Blvd. Suite 202, Great Neck, NY, 11021, USA. mlpilk01@gmail.com.
Gregory C LevineDepartment of Physics and Astronomy, Hofstra University, Hempstead, NY, 11549, USA.
Laura BennettDepartment of Physics and Astronomy, Hofstra University, Hempstead, NY, 11549, USA.
Harvey A WinklerDepartment of Obstetrics and Gynecology Division of Urogynecology, Northwell Health System, 865 Northern Blvd. Suite 202, Great Neck, NY, 11021, USA.
Dara F ShalomDepartment of Obstetrics and Gynecology Division of Urogynecology, Northwell Health System, 865 Northern Blvd. Suite 202, Great Neck, NY, 11021, USA.
Peter S FinamoreDepartment of Obstetrics and Gynecology Division of Urogynecology, Northwell Health System, Bayshore, NY, 11706, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introduction and hypothesisWe aimed to assess the pull-out strength of barbed and nonbarbed sutures used in sacrocolpopexy mesh fixation. We hypothesized there are no differences in the force needed to dislodge mesh from tissue using barbed and nonbarbed sutures of similar size.

methodsUsing the rectus fascia of three unembalmed cadavers, a 6 × 3 cm strip of polypropylene mesh was anchored to the fascia with sutures. The barbed sutures investigated were 2-0 V-Loc 180 (nine trials) and 3-0 bidirectional Quill™ SRS PDO (five trials). The nonbarbed sutures included 2-0 PDS (nine trials), CV-2 GORE-TEX (nine trials) and 2-0 Prolene (nine trials). The free-end of the mesh was anchored to a pulley system fixed to a tensiometer to measure the peak force applied at the moment of mesh dislodgement (termed the pull-out force). The pull-out force was recorded. Continuous variables are presented as medians and interquartile ranges (IQR). Analysis of variance was used to compare the forces across the suture types.

resultsThe highest pull-out force observed was with GORE-TEX (median 65.14 N, IQR 53.37-68.77 N) followed by Prolene (median 58.98 N, IQR 54.64-62.59 N), V-Loc (median 55.23 N, IQR 51.60-58.57 N), PDS (53.96 N, IQR 51.60-57.88 N), and Quill (44.44 N, IQR 17.27-47.38 N). All 2-0 and CV-2 caliber sutures had greater pull-out forces than 3-0 Quill sutures (p < 0.01). No significant differences in pull-out forces were observed between 2-0 and CV-2 caliber sutures (p > 0.05). In 35 of the 41 trials (85%), the mesh sheared from the tissue.

conclusionCV-2 ad 2-0 barbed and nonbarbed sutures had similar pull-out forces in an assessment of mesh fixation strength.

Indexed as

PolypropylenesSurgical MeshSuture TechniquesAnalysis of VarianceCadaverFemaleHumansMaterials TestingTensile StrengthPolypropylenesBarbed sutureMesh fixationPelvic organ prolapsePull-out forceSacrocolpopexy

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.