Evidence map›Paper›PMID 28979949›Full record

ArticleJACC. Basic to translational science2017

Brief Myocardial Ischemia Produces Cardiac Troponin I Release and Focal Myocyte Apoptosis in the Absence of Pathological Infarction in Swine.

Brian R Weil, Rebeccah F Young, Xiaomeng Shen, Gen Suzuki, Jun Qu, Saurabh Malhotra, John M Canty

Open access · goldAbstract read
In one paragraph

Article in JACC. Basic to translational science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed, 2 pooled it
8.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 2 syntheses or guidelines pooled it, 116 citations in OpenAlex.

  1. Pooled it
  2. Guidelines for experimental models of myocardial ischemia and infarction.American journal of physiology. Heart and circulatory physiology · 2018
    Guideline
  3. Metabolomics of early myocardial ischemia.Metabolomics : Official journal of the Metabolomic Society · 2023
    Trial
  4. Trial
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Clinical Biochemistry of Serum Troponin.Diagnostics (Basel, Switzerland) · 2024
    Review

3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Brian R WeilDepartment of Physiology & Biophysics, University at Buffalo, Buffalo, NY USA.
Rebeccah F YoungDepartment of Medicine, University at Buffalo, Buffalo, NY USA.
Xiaomeng ShenDepartment of Pharmaceutical Sciences, University at Buffalo, Buffalo, NY USA.
Gen SuzukiDepartment of Medicine, University at Buffalo, Buffalo, NY USA.
Jun QuDepartment of Pharmaceutical Sciences, University at Buffalo, Buffalo, NY USA.
Saurabh MalhotraDepartment of Medicine, University at Buffalo, Buffalo, NY USA.
John M CantyVA WNY Health Care System, University at Buffalo, Buffalo, NY USA.
University at Buffalo, State University of New York · US

Funding

University of Buffalo Clinical and Translational Science Institute - Supplement SchulyerUL1TR001412 · NCATS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI MURPHY, TIMOTHY F · 2015 to 2024
$33.8M
Metabolic Adaptation and Functional Recovery of Hibernating MyocardiumR01HL061610 · NHLBI · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI CANTY, JOHN M · 2000 to 2018
$6.0M
CHRONIC ADAPTATIONS TO MYOCARDIAL ISCHEMIAR01HL055324 · NHLBI · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI CANTY, JOHN M · 1996 to 2014
$4.2M
Amplification of Cardiosphere-Derived Cell TherapyF32HL114335 · NHLBI · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI WEIL, BRIAN RAYMOND · 2013 to 2015
$159k
Preventing and Reversing Interstitial Fibrosis in HFpEFI01BX002659 · VA · VA WESTERN NEW YORK HEALTHCARE SYSTEM · PI Brian Raymond Weil · 2016 to 2026
–
BLRD VA I01 BX002659NCATS NIH HHS UL1 TR001412NHLBI NIH HHS F32 HL114335NHLBI NIH HHS R01 HL055324NHLBI NIH HHS R01 HL061610
6 · The paper itself

Abstract

In a porcine model of brief ischemia leading to reversible stunning in the absence of tissue necrosis, we demonstrated delayed release of cTnI that exceeded the 99

Indexed as

Cardiac Troponin ICardiomyocyte ApoptosisMyocardial IschemiaMyocardial Stunning

Identifiers

PMID28979949
PMCPMC5624553
OpenAlexW2602446602

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.