Evidence map›Paper›PMID 28979944›Full record

ArticleACS central science2017

Virus-like Particle Display of the α-Gal Carbohydrate for Vaccination against

Anna Paula V Moura, Luiza C B Santos, Carlos Ramon Nascimento Brito, Edward Valencia, Caroline Junqueira, Adalberto A P Filho, Mauricio R V Sant'Anna, Nelder F Gontijo, Daniella C Bartholomeu, Ricardo T Fujiwara and 5 more

Open access · diamondAbstract read
In one paragraph

Article in ACS central science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed, 1 pooled it
8.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 1 synthesis or guideline pooled it, 78 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
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  5. Article
  6. Review
  7. Review
  8. Influenza virus-like particles presentingNanomedicine (London, England) · 2025
    Article
  9. Review
  10. Review
  11. Is Zebrafish a Good Model for the Alpha-Gal Syndrome?FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Review
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 2 countries.

Anna Paula V MouraInstituto de Ciencias Biologicas, Departamento de Parasitologia, Universidade Federal de Minas Gerais, Pampulha, Belo Horizonte, Minas Gerais, Brazil.
Luiza C B SantosInstituto de Ciencias Biologicas, Departamento de Parasitologia, Universidade Federal de Minas Gerais, Pampulha, Belo Horizonte, Minas Gerais, Brazil.
Carlos Ramon Nascimento BritoInstituto de Ciencias Biologicas, Departamento de Parasitologia, Universidade Federal de Minas Gerais, Pampulha, Belo Horizonte, Minas Gerais, Brazil.
Edward ValenciaInstituto de Ciencias Biologicas, Departamento de Parasitologia, Universidade Federal de Minas Gerais, Pampulha, Belo Horizonte, Minas Gerais, Brazil.
Caroline JunqueiraInstituto de Pesquisas René Rachou, Fundação Oswaldo Cruz, Belo Horizonte, Minas Gerais, Brazil.
Adalberto A P FilhoInstituto de Ciencias Biologicas, Departamento de Parasitologia, Universidade Federal de Minas Gerais, Pampulha, Belo Horizonte, Minas Gerais, Brazil.
Mauricio R V Sant'AnnaInstituto de Ciencias Biologicas, Departamento de Parasitologia, Universidade Federal de Minas Gerais, Pampulha, Belo Horizonte, Minas Gerais, Brazil.
Nelder F GontijoInstituto de Ciencias Biologicas, Departamento de Parasitologia, Universidade Federal de Minas Gerais, Pampulha, Belo Horizonte, Minas Gerais, Brazil.
Daniella C BartholomeuInstituto de Ciencias Biologicas, Departamento de Parasitologia, Universidade Federal de Minas Gerais, Pampulha, Belo Horizonte, Minas Gerais, Brazil.
Ricardo T FujiwaraInstituto de Ciencias Biologicas, Departamento de Parasitologia, Universidade Federal de Minas Gerais, Pampulha, Belo Horizonte, Minas Gerais, Brazil.
Ricardo T GazzinelliInstituto de Ciencias Biologicas, Departamento de Parasitologia, Universidade Federal de Minas Gerais, Pampulha, Belo Horizonte, Minas Gerais, Brazil.
Craig S McKaySchool of Chemistry and Biochemistry, School of Biology, Georgia Institute of Technology, Atlanta, Georgia 30332, United States.
Carlos A SanhuezaSchool of Chemistry and Biochemistry, School of Biology, Georgia Institute of Technology, Atlanta, Georgia 30332, United States.
M G FinnSchool of Chemistry and Biochemistry, School of Biology, Georgia Institute of Technology, Atlanta, Georgia 30332, United States.
Alexandre Ferreira MarquesInstituto de Ciencias Biologicas, Departamento de Parasitologia, Universidade Federal de Minas Gerais, Pampulha, Belo Horizonte, Minas Gerais, Brazil.
Universidade Federal de Minas Gerais · BRGeorgia Institute of Technology · USFundação Oswaldo Cruz · BR

Funding

Genetic and Chemically Programmed Nanoparticles for Prodrug TherapyR01GM101421 · NIGMS · GEORGIA INSTITUTE OF TECHNOLOGY · PI FINN, M.G. · 2013 to 2016
$1.1M
NIGMS NIH HHS R01 GM101421
6 · The paper itself

Abstract

Secreted and surface-displayed carbohydrates are essential for virulence and viability of many parasites, including for immune system evasion. We have identified the α-Gal trisaccharide epitope on the surface of the protozoan parasites

Identifiers

PMID28979944
PMCPMC5620979
OpenAlexW2755929605

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.