Evidence map›Paper›PMID 28979837›Full record

ArticleFEBS open bio2017

miR-30d is related to asbestos exposure and inhibits migration and invasion in NCI-H2452 cells.

Li Ju, Wei Wu, Xianhong Yin, Yun Xiao, Zhenyu Jia, Jianlin Lou, Min Yu, Shibo Ying, Tianhui Chen, Zhaoqiang Jiang and 4 more

Open access · goldAbstract read
In one paragraph

Article in FEBS open bio, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Li JuInstitute of Occupational Diseases Zhejiang Academy of Medical Sciences (ZJAMS) Hangzhou Zhejiang China.
Wei WuInstitute of Occupational Diseases Zhejiang Academy of Medical Sciences (ZJAMS) Hangzhou Zhejiang China.
Xianhong YinInstitute of Occupational Diseases Zhejiang Academy of Medical Sciences (ZJAMS) Hangzhou Zhejiang China.
Yun XiaoInstitute of Occupational Diseases Zhejiang Academy of Medical Sciences (ZJAMS) Hangzhou Zhejiang China.
Zhenyu JiaInstitute of Occupational Diseases Zhejiang Academy of Medical Sciences (ZJAMS) Hangzhou Zhejiang China.
Jianlin LouInstitute of Occupational Diseases Zhejiang Academy of Medical Sciences (ZJAMS) Hangzhou Zhejiang China.
Min YuInstitute of Occupational Diseases Zhejiang Academy of Medical Sciences (ZJAMS) Hangzhou Zhejiang China.
Shibo YingInstitute of Occupational Diseases Zhejiang Academy of Medical Sciences (ZJAMS) Hangzhou Zhejiang China.
Tianhui ChenInstitute of Occupational Diseases Zhejiang Academy of Medical Sciences (ZJAMS) Hangzhou Zhejiang China.
Zhaoqiang JiangInstitute of Occupational Diseases Zhejiang Academy of Medical Sciences (ZJAMS) Hangzhou Zhejiang China.
Wei LiExperimental Animal Center Zhejiang Academy of Medical Sciences (ZJAMS) Hangzhou Zhejiang China.
Junqiang ChenInstitute of Occupational Diseases Zhejiang Academy of Medical Sciences (ZJAMS) Hangzhou Zhejiang China.
Xing ZhangInstitute of Occupational Diseases Zhejiang Academy of Medical Sciences (ZJAMS) Hangzhou Zhejiang China.
Lijin ZhuInstitute of Occupational Diseases Zhejiang Academy of Medical Sciences (ZJAMS) Hangzhou Zhejiang China.
Zhejiang Academy of Medical Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pleural malignant mesothelioma (MM) is a highly aggressive tumor that is typically related to asbestos exposure and has a latency of 20-60 years. Several microRNA contribute to MM initiation and progression, but the mechanisms are not clear. Here, we found that miR-30d is downregulated in the pleural MM cell line NCI-H2452, in the plasma of asbestos-exposed individuals, and in asbestos-exposed mesothelial cells. Furthermore, we investigated the influence of the overexpression of miR-30d in pleural MM cells. We demonstrated that miR-30d overexpression could suppress pleural MM cell proliferation, migration, and invasion

Indexed as

asbestosmesotheliomamicroRNAmicroRNA‐30dneoplasm invasiveness

Identifiers

PMID28979837
PMCPMC5623706
OpenAlexW2743075338

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.