Evidence map›Paper›PMID 28979718›Full record

ArticleWorld journal of gastrointestinal oncology2017

Characterisation and risk assessment of venous thromboembolism in gastrointestinal cancers.

Robert L Metcalf, Eamon Al-Hadithi, Nicholas Hopley, Thomas Henry, Clare Hodgson, Antony McGurk, Wasat Mansoor, Jurjees Hasan

Open access · hybridAbstract read
In one paragraph

Article in World journal of gastrointestinal oncology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. The Role of KRAS Mutation in Colorectal Cancer-Associated Thrombosis.International journal of molecular sciences · 2023
    Article
  6. Article
  7. Propensity score-matching analysis comparing safety outcomes of appetite-stimulating medications in oncology patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Cancer-associated thrombosis: The search for the holy grail continues.Research and practice in thrombosis and haemostasis · 2018
    Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Robert L MetcalfDepartment of Medical Oncology, the Christie NHS Foundation Trust, Manchester M20 4BX, United Kingdom.
Eamon Al-HadithiDepartment of Medical Oncology, the Christie NHS Foundation Trust, Manchester M20 4BX, United Kingdom.
Nicholas Hopleythe University of Manchester, Manchester M13 9PL, United Kingdom.
Thomas Henrythe University of Manchester, Manchester M13 9PL, United Kingdom.
Clare HodgsonDepartment of Biostatistics, the Christie NHS Foundation Trust, Manchester M20 4BX, United Kingdom.
Antony McGurkDepartment of Quality and Standards, the Christie NHS Foundation Trust, Manchester M20 4BX, United Kingdom.
Wasat MansoorDepartment of Medical Oncology, the Christie NHS Foundation Trust, Manchester M20 4BX, United Kingdom.
Jurjees HasanDepartment of Medical Oncology, the Christie NHS Foundation Trust, Manchester M20 4BX, United Kingdom. jurjees.hasan@christie.nhs.uk.
The Christie NHS Foundation Trust · GBUniversity of Manchester · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo characterise venous thromboembolism (VTE) in gastrointestinal cancer and assess the clinical utility of risk stratification scoring.

methodsWe performed a retrospective analysis using electronic patient records of 910 gastro-oesophageal (GO) cancer and 1299 colorectal cancer (CRC) patients referred to a tertiary cancer centre to identify the incidence of VTE, its relationship to chemotherapy and impact on survival. VTE risk scores were calculated using the Khorana index. Patients were classified as low risk (0 points), intermediate risk (1 to 2 points) or high risk (3 points). Data was analysed to determine the sensitivity of the Khorana score to predict VTE.

resultsThe incidence of VTE was 8.9% for CRC patients and 9.7% for GO cancer patients. Pulmonary emboli (PE) were more common in advanced than in localised CRC (50%

conclusionThe Khorana score has low sensitivity for thrombotic events in CRC and cannot discriminate low risk patients in high risk cancer sites such as GO cancer.

Indexed as

Colorectal cancerDeep venous thrombosisGastro-oesophageal cancerOesophageal cancerPulmonary embolismThrombo-embolism

Identifiers

PMID28979718
PMCPMC5605336
OpenAlexW2755973232

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.