Evidence map›Paper›PMID 28979514›Full record

ArticleJournal of the Intensive Care Society2016

A case for stopping the early withdrawal of life sustaining therapies in patients with devastating brain injuries.

Alex R Manara, Ian Thomas, Richard Harding

Abstract read
In one paragraph

Article in Journal of the Intensive Care Society, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Determining the impact of timing and of clinical factors during end-of-life decision-making in potential controlled donation after circulatory death donors.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2020
    Observational
  8. Article
  9. Article
  10. Article
  11. Intensive care for organ preservation: A four-stage pathway.Journal of the Intensive Care Society · 2019
    Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Treatment-limiting decisions in patients with severe traumatic brain injury in a Norwegian regional trauma center.Scandinavian journal of trauma, resuscitation and emergency medicine · 2017
    Article
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Alex R ManaraNorth Bristol NHS Trust, Bristol, UK.
Ian ThomasNorth Bristol NHS Trust, Bristol, UK.
Richard HardingWye Valley NHS Trust, Hereford, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Early prognostication in patients with a devastating brain injury is not always accurate and can lead to inappropriate decisions. We present case histories to support the recent recommendations of the Neurocritical Care Society that treatment withdrawal decisions should be delayed by up to 72 h in these patients. Development of pathways incorporating these recommendations can improve prognostication, enhance end of life care given to these patients and their families, and increase the opportunities to explore the donation wishes of more patients. They may also standardise the approach to decision making in the same way as the recommendations for management of patients after out of hospital cardiac arrest have done.

Indexed as

critical care managementDevastating brain injuryend of life careneurocritical careorgan donation

Identifiers

PMID28979514
PMCPMC5624473

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.