ArticleFrontiers in microbiology2017
Illumina Sequencing Approach to Characterize Thiamine Metabolism Related Bacteria and the Impacts of Thiamine Supplementation on Ruminal Microbiota in Dairy Cows Fed High-Grain Diets.
Article in Frontiers in microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
72 citing papers in PubMed, 1 synthesis or guideline pooled it, 148 citations in OpenAlex.
- Gut microbiota bridges dietary nutrients and host immunity.Science China. Life sciences · 2023Pooled it
- Integrated Rumen Metabolomics and Metagenomics Reveal Microbe-Metabolite Signatures Associated with Heat Tolerance in Dairy Cows.Animals : an open access journal from MDPI · 2026Article
- Rumen Mycobiome Thiamine Metabolism Contributes to Subacute Rumen Acidosis Tolerance in Goats Through Enhancing Epithelial Cell Proliferation via IGFBP2/IGF1 Axis Activation.Exploration (Beijing, China) · 2026Article
- Determination of the Modulatory Effects of Selenium-Enriched Egg Powder on the Physiological Immune Response and Cecal Microbiota of Kunming Mice.Foods (Basel, Switzerland) · 2026Article
- Metagenomic Insights into the Modulatory Effects of Thiamine Supplementation for Treating Subclinical Ketosis Dairy Cows.Animals : an open access journal from MDPI · 2026Article
- Metabolomic insights into thiamine-mediated metabolism in treating subclinical ketosis in dairy cows.Frontiers in veterinary science · 2026Article
- Effects of flammulina velutipes stipe wastes on egg performance, cecum microbiota, intestinal barrier and serum immune response of laying hens.BMC veterinary research · 2025Article
- Ruminal dysbiosis-induced mastitis: new insight into the pathogenesis of mastitis.Journal of animal science and biotechnology · 2025Review
- Understanding the differences in rumen bacteria and their impact on dairy cows' production performance: A review.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2025Review
- Effects of fiber concentrations and fermentation rates on reproductive performance, nutrient digestibility, immune response, and microbiota of lactating sows.Journal of animal science · 2025Article
- Effects of feeding high-moisture corn on growth performance and rumen metabolism in young Simmental bulls.Frontiers in veterinary science · 2025Article
- Effects of glycyrrhetinic acid on production performance, serum biochemical indexes, ruminal parameters, and rumen microflora of beef cattle.Frontiers in veterinary science · 2025Article
- Efficacy of sclareol based on 16S rDNA sequencing in modulating gut microbiota composition in estradiol-treated mice.Bioscience of microbiota, food and health · 2025Article
- Fluctuations in dietary crude protein content affect rumen bacterial community and metabolome in Holstein dairy cows.Frontiers in veterinary science · 2025Article
- Mediterranean diet and associations with the gut microbiota and pediatric-onset multiple sclerosis using trivariate analysis.Communications medicine · 2024Article
- Rumen and hindgut microbiome regulate average daily gain of preweaning Holstein heifer calves in different ways.Microbiome · 2024Article
- Network analysis of gut microbial communities reveal key genera for a multiple sclerosis cohort with Mycobacterium avium subspecies paratuberculosis infection.Gut pathogens · 2024Article
- Effect of Adding Yeast Cultures to High-Grain Conditions on Production Performance, Rumen Fermentation Profile, Microbial Abundance, and Immunity in Goats.Animals : an open access journal from MDPI · 2024Article
- Comparative Study of Bacterial Microbiota Differences in the Rumen and Feces of Xinjiang Brown and Holstein Cattle.Animals : an open access journal from MDPI · 2024Article
- Effects of dietary forage neutral detergent fiber and rumen degradable starch ratios on chewing activity, ruminal fermentation, ruminal microbes and nutrient digestibility of Hu sheep fed a pelleted total mixed ration.Journal of animal science · 2024Article
12 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The requirements of thiamine in adult ruminants are mainly met by ruminal bacterial synthesis, and thiamine deficiencies will occur when dairy cows overfed with high grain diet. However, there is limited knowledge with regard to the ruminal thiamine synthesis bacteria, and whether thiamine deficiency is related to the altered bacterial community by high grain diet is still unclear. To explore thiamine synthesis bacteria and the response of ruminal microbiota to high grain feeding and thiamine supplementation, six rumen-cannulated Holstein cows were randomly assigned into a replicated 3 × 3 Latin square design trial. Three treatments were control diet (CON, 20% dietary starch, DM basis), high grain diet (HG, 33.2% dietary starch, DM basis) and high grain diet supplemented with 180 mg thiamine/kg DMI (HG+T). On day 21 of each period, rumen content samples were collected at 3 h postfeeding. Ruminal thiamine concentration was detected by high performance liquid chromatography. The microbiota composition was determined using Illumina MiSeq sequencing of 16S rRNA gene. Cows receiving thiamine supplementation had greater ruminal pH value, acetate and thiamine content in the rumen. Principal coordinate analysis and similarity analysis indicated that HG feeding and thiamine supplementation caused a strong shift in bacterial composition and structure in the rumen. At the genus level, compared with CON group, the relative abundances of 19 genera were significantly changed by HG feeding. Thiamine supplementation increased the abundance of cellulolytic bacteria including
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