Evidence map›Paper›PMID 28979210›Full record

ArticleFrontiers in physiology2017

Chronic Hypobaric Hypoxia Modulates Primary Cilia Differently in Adult and Fetal Ovine Kidneys.

Kiumars Shamloo, Juan Chen, Jasmine Sardar, Rinzhin T Sherpa, Rajasekharreddy Pala, Kimberly F Atkinson, William J Pearce, Lubo Zhang, Surya M Nauli

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.2field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Advancing high-altitude medicine: a model for the future.Signal transduction and targeted therapy · 2026
    Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Phosphosite T674A mutation in kinesin family member 3A fails to reproduce tissue and ciliary defects characteristic of CILK1 loss of function.Developmental dynamics : an official publication of the American Association of Anatomists · 2021
    Article
  8. Intraflagellar Transport Proteins as Regulators of Primary Cilia Length.Frontiers in cell and developmental biology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Kiumars ShamlooDepartment of Biomedical and Pharmaceutical Sciences, Chapman UniversityIrvine, CA, United States.
Juan ChenDepartment of Biomedical and Pharmaceutical Sciences, Chapman UniversityIrvine, CA, United States.
Jasmine SardarDepartment of Biomedical and Pharmaceutical Sciences, Chapman UniversityIrvine, CA, United States.
Rinzhin T SherpaDepartment of Biomedical and Pharmaceutical Sciences, Chapman UniversityIrvine, CA, United States.
Rajasekharreddy PalaDepartment of Biomedical and Pharmaceutical Sciences, Chapman UniversityIrvine, CA, United States.
Kimberly F AtkinsonDepartment of Biomedical and Pharmaceutical Sciences, Chapman UniversityIrvine, CA, United States.
William J PearceDepartments of Basic Sciences, Physiology and Pharmacology, Lawrence D. Longo MD Center for Perinatal Biology, Loma Linda University School of MedicineLoma Linda, CA, United States.
Lubo ZhangDepartments of Basic Sciences, Physiology and Pharmacology, Lawrence D. Longo MD Center for Perinatal Biology, Loma Linda University School of MedicineLoma Linda, CA, United States.
Surya M NauliDepartment of Biomedical and Pharmaceutical Sciences, Chapman UniversityIrvine, CA, United States.
Chapman University · USLoma Linda University · USUniversity of California, Irvine · US

Funding

Uterine Vascular Adaptation to Pregnancy and Chronic HypoxiaP01HD083132 · NICHD · LOMA LINDA UNIVERSITY · PI DUCSAY, CHARLES A · 2016 to 2020
$6.3M
NICHD NIH HHS P01 HD083132
6 · The paper itself

Abstract

Hypoxic environments at high altitude have significant effects on kidney injury. Following injury, renal primary cilia display length alterations. Primary cilia are mechanosensory organelles that regulate tubular architecture. The effect of hypoxia on cilia length is still controversial in cultured cells, and no corresponding

Indexed as

ciliumkidney injurymechanosensorpO2renal fibrosisshear-stresssheep

Identifiers

PMID28979210
PMCPMC5611369
OpenAlexW2756057406

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.