ReviewFrontiers in systems neuroscience2017
Speed and Oscillations: Medial Septum Integration of Attention and Navigation.
Review in Frontiers in systems neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Predictive goal coding by dentate gyrus somatostatin-expressing interneurons in male mice.Nature communications · 2025Article
- Kisspeptin fiber and receptor distribution analysis suggests its potential role in central sensorial processing and behavioral state control.Journal of neuroendocrinology · 2025Article
- Neural and sensory basis of homing behaviour in the invasive cane toad,Proceedings. Biological sciences · 2025Article
- Neural and sensory basis of homing behavior in the invasive cane toad,bioRxiv : the preprint server for biology · 2025Article
- Theta oscillations optimize a speed-precision trade-off in phase coding neurons.PLoS computational biology · 2024Article
- Interplay of hippocampal long-term potentiation and long-term depression in enabling memory representations.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024Review
- Grid cells: the missing link in understanding Parkinson's disease?Frontiers in neuroscience · 2024Article
- Medial and dorsal lateral septum involving social disruption stress-primed escalation in acid-induced writhes.Frontiers in molecular neuroscience · 2023Article
- Inhibitory hippocampus-medial septum projection controls locomotion and exploratory behavior.Frontiers in synaptic neuroscience · 2023Article
- Entrance-sealing behavior in the home cage: a defensive response to potential threats linked to the serotonergic system and manifestation of repetitive/stereotypic behavior in mice.Frontiers in behavioral neuroscience · 2023Article
- Optogenetic Suppression of Lateral Septum Somatostatin Neurons Enhances Hippocampus Cholinergic Theta Oscillations and Local Synchrony.Brain sciences · 2022Article
- Medial septum activation improves strategy switching once strategies are well-learned via bidirectional regulation of dopamine neuron population activity.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022Article
- Frequency-specific medial septal nucleus deep brain stimulation improves spatial memory in MK-801-treated male rats.Neurobiology of disease · 2022Article
- Basal Forebrain Impairment: Understanding the Mnemonic Function of the Septal Region Translates in Therapeutic Advances.Frontiers in neural circuits · 2022Review
- The Medial Septum as a Potential Target for Treating Brain Disorders Associated With Oscillopathies.Frontiers in neural circuits · 2021Review
- Cooling of Medial Septum Reveals Theta Phase Lag Coordination of Hippocampal Cell Assemblies.Neuron · 2020Article
- Cholinergic modulation of spatial learning, memory and navigation.The European journal of neuroscience · 2018Review
- Review
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Authors and funding
1 author.
Funding
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Abstract
Several cortical and diencephalic limbic brain regions incorporate neurons that fire in correlation with the speed of whole-body motion, also known as linear velocity. Besides the field mapping and head-directional information, the linear velocity is among the major signals that guide animal's spatial navigation. Large neuronal populations in the same limbic regions oscillate with theta rhythm during spatial navigation or attention episodes; and the frequency of theta also correlates with linear velocity. A functional similarity between these brain areas is that their inactivation impairs the ability to form new spatial memories; whereas an anatomical similarity is that they all receive projections from medial septum-diagonal band of Broca complex. We review recent findings supporting the model that septal theta rhythm integrates different sensorimotor signals necessary for spatial navigation. The medial septal is described here as a circuitry that mediates experience-dependent balance of sustained attention and path integration during navigation. We discuss the hypothesis that theta rhythm serves as a key mechanism for the aligning of intrinsic spatial representation to: (1) rapid change of position in the spatial environment; (2) continuous alteration of sensory signals throughout navigation; and (3) adapting levels of attentional behavior. The synchronization of these spatial, somatosensory and neuromodulatory signals is proposed here to be anatomically and physiologically mediated by the medial septum.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.