Evidence map›Paper›PMID 28979158›Full record

ArticleJournal of pain research2017

The Central Sensitization Inventory validated and adapted for a Brazilian population: psychometric properties and its relationship with brain-derived neurotrophic factor.

Wolnei Caumo, Luciana C Antunes, Jéssica Lorenzzi Elkfury, Evelyn G Herbstrith, Raquel Busanello Sipmann, Andressa Souza, Iraci Ls Torres, Vinicius Souza Dos Santos, Randy Neblett

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of pain research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
79citing papers in PubMed, 3 pooled it
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

79 citing papers in PubMed, 3 syntheses or guidelines pooled it, 182 citations in OpenAlex.

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  17. Kinesiophobia and Work Disability in Fibromyalgia: Cognitive Mediation in a Population-Based Study of Women.European journal of investigation in health, psychology and education · 2026
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19 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

Wolnei CaumoPostgraduate Program in Medical Sciences, School of Medicine.
Luciana C AntunesPostgraduate Program in Medical Sciences, School of Medicine.
Jéssica Lorenzzi ElkfuryPostgraduate Program in Medical Sciences, School of Medicine.
Evelyn G HerbstrithSchool of Psychology, Pontifícia Universidade Católica do Rio Grande do Sul.
Raquel Busanello SipmannSchool of Medicine, Universidade Federal do Rio Grande do Sul.
Andressa SouzaPostgraduate Program in Health and Human Development, La Salle University Center, Canoas.
Iraci Ls TorresPostgraduate Program in Medical Sciences, School of Medicine.
Vinicius Souza Dos SantosPostgraduate Program in Medical Sciences, School of Medicine.
Randy NeblettPRIDE Research Foundation, Dallas, TX, USA.
Universidade Federal do Rio Grande do Sul · BRInternational Neuromodulation Society · USPontifícia Universidade Católica do Rio Grande do Sul · BRProductive Rehabilitation Institute of Dallas for Ergonomics · USUniversidade La Salle · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe primary aim was to assess the psychometric properties (including internal consistency, construct validity, reproducibility, and factor structure) of the Central Sensitization Inventory (CSI), adapted and validated for a Brazilian population (CSI-BP). Additionally, we evaluated the relationship between the CSI-BP and the serum brain-derived neurotrophic factor (BDNF) and determined if the symptoms elicited by the CSI-BP discriminate between subjects who do/do not respond to the conditioned pain modulation (CPM) task, as assessed by change in numeric pain scale (0-10) score. PATIENTS AND

methodsA cross-sectional study was conducted in a pain clinic in a tertiary teaching hospital. A total of 222 adults with chronic musculoskeletal pain and 63 healthy control subjects completed the CSI-BP and the Brazilian Portuguese pain-catastrophizing scale (BP-PCS). A team of experts translated the CSI according to the international guidelines. Test-retest, item analysis, convergent validity, and factor analysis were performed. Later, a random subsample (n=77) was used to correlate the CSI-BP adjusted index with change in numeric pain-scale score during the CPM task and a BDNF blood sample.

resultsThe CSI-BP presented strong psychometric properties (test-retest reliability 0.91, Cronbach's

conclusionThe CSI-BP was found to be a psychometrically strong and reliable instrument, with primary evidence of validity. Higher scores on the CSI-BP were correlated positively with serum BDNF and with greater dysfunction of the descending pain-modulatory system.

Indexed as

central sensitizationchronic painconditioned pain modulationconfirmatory factor analysiscross-cultural adaptationserum brain-derived neurotrophic factor

Identifiers

PMID28979158
PMCPMC5589103
OpenAlexW2751578168

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.