Evidence map›Paper›PMID 28979141›Full record

ArticleOncoTargets and therapy2017

Genome-scale analysis to identify prognostic markers in patients with early-stage pancreatic ductal adenocarcinoma after pancreaticoduodenectomy.

Xiwen Liao, Ketuan Huang, Rui Huang, Xiaoguang Liu, Chuangye Han, Long Yu, Tingdong Yu, Chengkun Yang, Xiangkun Wang, Tao Peng

Abstract read
In one paragraph

Article in OncoTargets and therapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed.

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  5. SLA2 is a prognostic marker in HNSCC and correlates with immune cell infiltration in the tumor microenvironment.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024
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  6. Fixing the GAP: The role of RhoGAPs in cancer.European journal of cell biology · 2022
    Review
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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

10 authors.

Xiwen Liao *Department of Hepatobiliary Surgery, The First Affiliated Hospital of Guangxi Medical University.
Ketuan Huang *Department of Hepatobiliary Surgery, The First Affiliated Hospital of Guangxi Medical University.
Rui HuangDepartment of Hematology, The First Affiliated Hospital of Guangxi Medical University, Nanning.
Xiaoguang LiuDepartment of Hepatobiliary Surgery, The First Affiliated Hospital of Guangxi Medical University.
Chuangye HanDepartment of Hepatobiliary Surgery, The First Affiliated Hospital of Guangxi Medical University.
Long YuDepartment of Hepatobiliary Surgery, The First Affiliated Hospital of Guangxi Medical University.
Tingdong YuDepartment of Hepatobiliary Surgery, The First Affiliated Hospital of Guangxi Medical University.
Chengkun YangDepartment of Hepatobiliary Surgery, The First Affiliated Hospital of Guangxi Medical University.
Xiangkun WangDepartment of Hepatobiliary Surgery, The First Affiliated Hospital of Guangxi Medical University.
Tao PengDepartment of Hepatobiliary Surgery, The First Affiliated Hospital of Guangxi Medical University.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMolecular analysis is a promising source of clinically useful prognostic biomarkers. The aim of this investigation was to identify prognostic biomarkers for patients with early-stage pancreatic ductal adenocarcinoma (PDAC) after pancreaticoduodenectomy.

methodsAn RNA sequencing dataset of PDAC was obtained from The Cancer Genome Atlas. Survival analysis and weighted gene co-expression network analysis were used to investigate the prognostic markers of early-stage PDAC after pancreaticoduodenectomy.

resultsUsing whole genome expression level screening, we identified 1,238 markers that were related to the prognosis of PDAC after pancreaticoduodenectomy, and identified 9 hub genes (

conclusionOur results have provided a new prospect for prognostic biomarkers of PDAC after pancreaticoduodenectomy, and may have a value in clinical application.

Indexed as

pancreatic ductal adenocarcinomapancreaticoduodenectomyprognosticTCGAWGCNA

Identifiers

PMID28979141
PMCPMC5602474

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.