Observational studyInternational journal of chronic obstructive pulmonary disease2017
Impact of overweight and obesity on acute exacerbations of COPD - subgroup analysis of the Taiwan Obstructive Lung Disease cohort.
Observational study in International journal of chronic obstructive pulmonary disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed, 3 syntheses or guidelines pooled it, 46 citations in OpenAlex.
- Pooled it
- Prognostic risk factors for moderate-to-severe exacerbations in patients with chronic obstructive pulmonary disease: a systematic literature review.Respiratory research · 2022Pooled it
- BMI is associated with FEVRespiratory research · 2019Pooled it
- Risk factors for exacerbations and pneumonia in patients with chronic obstructive pulmonary disease: a pooled analysis.Respiratory research · 2020Trial
- Severe Obesity and Alpha-1 Antitrypsin Deficiency-Associated COPD: A Dual Burden on Health and Quality of Life.Chronic obstructive pulmonary diseases (Miami, Fla.) · 2026Article
- Exploring the obesity paradox in chronic respiratory disease: the mediating effect of triglyceride-glucose index on mortality.NPJ primary care respiratory medicine · 2025Article
- Body Mass Index and Lung Function in Hospitalized Severe AECOPD Patients: Investigating Nonlinear Associations and the Role of Hemoglobin.International journal of chronic obstructive pulmonary disease · 2025Article
- COPD and Metabolic Syndrome: Unanswered Questions and Opportunities for Innovation.Chronic obstructive pulmonary diseases (Miami, Fla.) · 2024Article
- Impact of Body Mass Index on Risk of Exacerbation in Patients With COPD: A Systematic Review and Meta-Analysis.Chronic obstructive pulmonary diseases (Miami, Fla.) · 2024Article
- Clinical Characteristics of Overweight Patients With Acute Exacerbation Chronic Obstructive Pulmonary Disease (AECOPD).The clinical respiratory journal · 2024Article
- Adipocyte dysfunction promotes lung inflammation and aberrant repair: a potential target of COPD.Frontiers in endocrinology · 2023Article
- The clinical characteristics and treatment response of patients with chronic obstructive pulmonary disease with low body mass index.Frontiers in pharmacology · 2023Article
- Obesity Paradox in Lung Diseases: What Explains It?Obesity facts · 2023Review
- The Obesity Paradox in Chronic Heart Disease and Chronic Obstructive Pulmonary Disease.Cureus · 2022Review
- Association of body mass index and COPD exacerbation among patients with chronic bronchitis.Respiratory research · 2022Observational
- Effects of Obstructive Sleep Apnea and Obesity on 30-Day Readmissions in Patients with Chronic Obstructive Pulmonary Disease: A Cross-Sectional Mediation Analysis.Annals of the American Thoracic Society · 2022Article
- Mortality and Exacerbation Risk by Body Mass Index in Patients with COPD in TIOSPIR and UPLIFT.Annals of the American Thoracic Society · 2022Article
- Determinants of Pulmonary Emphysema Severity in Taiwanese Patients with Chronic Obstructive Pulmonary Disease: An Integrated Epigenomic and Air Pollutant Analysis.Biomedicines · 2021Article
- Racial Disparities in Health Risk Indicators Reported by Alabamians Diagnosed with COPD.International journal of environmental research and public health · 2021Article
- Nutritional status and quality of life in interstitial lung disease: a prospective cohort study.BMC pulmonary medicine · 2021Article
Corrections and comments
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Authors and funding
4 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeA low body mass index (BMI) is a poor prognostic marker of acute exacerbations and mortality in patients with COPD. However, the impact of overweight and obesity on COPD-related outcomes is uncertain. The aim of this study was to examine whether a high BMI is associated with the frequent exacerbator phenotype (≥2/year) in Taiwanese patients with COPD. PATIENTS AND
methodsData were obtained from the Taiwan Obstructive Lung Disease study, a retrospective, observational nationwide survey of COPD patients conducted at 12 hospitals in Taiwan. Multivariate logistic regression models were used to explore the association between BMI and other factors with the frequency of COPD exacerbations in these patients.
resultsAmong the whole study cohort (n=1,096), 735 (67.1%) had no exacerbations and 148 (13.5%) were frequent exacerbators in the previous year. The BMI values of the patients with 0, 1, and ≥2 exacerbations were 23.6, 23.5, and 22.6 kg/m
conclusionOur results suggest that overweight and obesity are associated with a lower frequency of COPD exacerbations in Taiwan.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.