ArticleClinical ophthalmology (Auckland, N.Z.)2017
Long-term evaluation of spontaneous release of epiretinal membrane and its possible pathogenesis.
Article in Clinical ophthalmology (Auckland, N.Z.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 13 citations in OpenAlex.
- Spontaneous separation of epiretinal membrane associated with retinal hemangioblastoma: a case report with 10-year follow-up.American journal of ophthalmology case reports · 2025Article
- Spontaneous epiretinal membrane resolution: mechanisms, outcomes, and implications for clinical management.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025Review
- Spontaneous separation of secondary epiretinal membrane after vitrectomy for retinal detachment.American journal of ophthalmology case reports · 2024Article
- Article
- Photocoagulation-associated spontaneous release of epiretinal membrane secondary to retinal vascular tumor: case series of 8 cases.Lasers in medical science · 2022Article
- Rapid Morphological Restoration of Normal Foveal Contour After Spontaneous Epiretinal Membrane Separation from Retina in Eye with Macular Pseudohole: A Case Report.International medical case reports journal · 2021Article
- Long-term natural history of the idiopathic epiretinal membrane in children and young adults.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2020Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo investigate the characteristics in spontaneous release of epiretinal membrane (ERM) during watchful waiting and to introduce a possible mechanism of pathogenesis as a photo essay.
methodsRecords from all patients with ERM were obtained from Osaka Medical College Hospital from January 2001 to October 2012. Visual acuity (VA), fundus photo, and optical coherence tomography (OCT) were reviewed using the medical records. For statistical analysis, VA measured with a Landolt chart was converted to the logarithm of the minimum angle of resolution (logMAR). To investigate the pathogenesis of ERM, tryptase activity in vitreous, which plays a role in tissue fibrosis and remodeling, was measured in patients that underwent a vitrectomy for ERM, macular hole, and proliferative diabetic retinopathy (PDR).
resultsERM was observed in 604 patients and spontaneous release of the ERM was observed in 13 patients with 14 eyes (four males and nine females, aged 33-78 years). Among the 14 eyes, mean VA did not change significantly through the release of the ERMs (0.17±0.18 before and 0.24±0.40 after release,
conclusionFundus photos of ERM auto-peeling were taken during long-term follow-up. Spontaneous release of ERM is possibly involved in vitreous traction or membrane contraction. In addition, tryptase may be involved in the development and contraction of ERM.
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