Evidence map›Paper›PMID 28978977›Full record

ArticleInternational journal of obesity (2005)2018

Body mass index trajectories in childhood is predictive of cardiovascular risk: results from the 23-year longitudinal Georgia Stress and Heart study.

G Hao, X Wang, F A Treiber, G Harshfield, G Kapuku, S Su

Abstract read
In one paragraph

Article in International journal of obesity (2005), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 3 pooled it
7.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 3 syntheses or guidelines pooled it, 47 citations in OpenAlex.

  1. Methods for the economic evaluation of obesity prevention dietary interventions in children: A systematic review and critical appraisal of the evidence.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2022
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  6. Weight Status Transitions and Validation of an Obesity Model for Aboriginal and Torres Strait Islander Children and Adolescents.Medical decision making : an international journal of the Society for Medical Decision Making · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

G HaoDepartment of Population Health Sciences, Medical College of Georgia, Augusta University, Augusta, GA, USA.ORCID 0000-0003-3780-0223
X WangDepartment of Population Health Sciences, Medical College of Georgia, Augusta University, Augusta, GA, USA.
F A TreiberTechnology Applications Center for Healthful Lifestyles, Colleges of Nursing and Medicine, Medical University of South Carolina, Charleston, SC, USA.
G HarshfieldDepartment of Population Health Sciences, Medical College of Georgia, Augusta University, Augusta, GA, USA.
G KapukuDepartment of Population Health Sciences, Medical College of Georgia, Augusta University, Augusta, GA, USA.
S SuDepartment of Population Health Sciences, Medical College of Georgia, Augusta University, Augusta, GA, USA.
Augusta University · USMedical University of South Carolina · US

Funding

Vascular and renal responses to stressP01HL069999 · NHLBI · MEDICAL COLLEGE OF GEORGIA (MCG) · PI GEORGE, VARGHESE · 2002 to 2018
$31.1M
Epigenetic Basis of Obesity Induced Cardiovascular Disease and Type 2 DiabetesR01HL105689 · NHLBI · AUGUSTA UNIVERSITY · PI WANG, XIAOLING · 2011 to 2015
$3.3M
Epigenetic Response to Early Life Stress and the Impact on Cardiovascular HealthR01HL125577 · NHLBI · AUGUSTA UNIVERSITY · PI SU, SHAOYONG · 2015 to 2018
$1.5M
NHLBI NIH HHS P01 HL069999NHLBI NIH HHS R01 HL105689NHLBI NIH HHS R01 HL125577
6 · The paper itself

Abstract

The childhood high body mass index (BMI) is associated with cardiovascular risk, but the association between childhood BMI trajectory patterns and cardiovascular risk remains unclear. The purposes of this study are to identify subgroups of individuals with similar trajectories in BMI during childhood, and to determine the relationship of childhood BMI trajectories with subclinical cardiovascular disease in young adulthood, indexed by intima-media thickness (IMT) and left ventricular mass index (LVMI). The participants were from the Georgia Stress and Heart (GSH) study. A total of 626 participants with BMI measured 3-12 times during childhood (5-18 years old) were included. By using latent class models, three trajectory groups in BMI were identified, including high increasing (HI), moderate increasing (MI) and normal group. We found that childhood trajectory of BMI was significantly associated with IMT and LVMI in young adulthood even after adjustment for BMI in young adulthood. Our results suggested that different BMI trajectory patterns exist during childhood. We for the first time reported the association between childhood BMI trajectory patterns and subclinical cardiovascular risk in young adulthood, indicating that monitoring trajectories of BMI from childhood may help to identify a high cardiovascular risk population in early life.

Indexed as

Body Mass IndexAdolescentCardiovascular DiseasesCarotid Intima-Media ThicknessChildChild, PreschoolGeorgiaHeart VentriclesHumansLongitudinal StudiesRisk Factors

Identifiers

PMID28978977
PMCPMC5886821
OpenAlexW2761545139

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.