Evidence map›Paper›PMID 28978912›Full record

ArticleScientific reports2017

Gender Disparities in Lipid Goal Attainment among Type 2 Diabetes Outpatients with Coronary Heart Disease: Results from the CCMR-3B Study.

Xiaomei Zhang, Linong Ji, Xingwu Ran, Benli Su, Qiuhe Ji, Dayi Hu

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In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Xiaomei ZhangPeking University International Hospital, Department of Endocrinology and Metabolism, Beijing, 102206, China.
Linong JiPeking University People's Hospital, Department of Endocrinology and Metabolism, Beijing, 100044, China. jiln@bjmu.edu.cn.
Xingwu RanWest China Hospital, Sichuan University, Department of Endocrinology and Metabolism, Chengdu, 610041, China.
Benli SuThe Second Affiliated Hospital of Dalian Medical University, Department of Endocrinology, Dalian, 116027, China.
Qiuhe JiXijing Hospital, Forth Military Medical University, Department of Endocrinology, Xi'an, 710032, China.
Dayi HuPeking University People's Hospital, Department of Cardiology, Beijing, 100044, China.
Peking University · CNPeking University People's Hospital · CNSecond Affiliated Hospital of Dalian Medical University · CNSichuan University · CNXijing Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Our study was aimed to investigate the gender disparities in lipid goal attainment among type 2 diabetes outpatients with concomitant coronary heart disease (CHD) and explore potential risk factors. We performed the present analysis using data from a nationally representative epidemiologic study. The therapeutic goal was defined as achieving a low-density lipoprotein cholesterol (LDL-C) <1.8 mmol/L. A total of 1721 male and 2072 female type 2 diabetes outpatients with established CHD were identified. Compared with men, women had higher levels of total cholesterol (4.98 vs. 4.46 mmol/L; p < 0.001), LDL-C (2.82 vs. 2.54 mmol/L; p < 0.001), and triglycerides (2.02 vs. 1.79 mmol/L; p < 0.001), but not hemoglobin A1c (7.47% vs. 7.50%; p = 0.597). The proportion of women received lipid-lowering therapy was lower (38.1% vs. 48.2%; p < 0.001). The percentages of patients who achieved the LDL-C goal were higher among men. Multivariable regression analysis indicated that the odds ratio for lipid goal attainment due to the gender difference was 0.61 after adjusting confounders. The inability to achieve LDL-C goals in women with type 2 diabetes and CHD is apparently greater than that in men. This finding underscores the importance of initiatives to establish a more aggressive lipid management strategy for women to overcome gender imbalances.

Indexed as

AgedAnticholesteremic AgentsCholesterol, HDLCholesterol, LDLCoronary DiseaseDiabetes Mellitus, Type 2FemaleGlycated HemoglobinHumansHydroxymethylglutaryl-CoA Reductase InhibitorsLipidsMaleMiddle AgedOutpatientsRisk FactorsSex CharacteristicsAnticholesteremic AgentsCholesterol, HDLCholesterol, LDLGlycated Hemoglobinhemoglobin A1c protein, humanHydroxymethylglutaryl-CoA Reductase InhibitorsLipidsTriglycerides

Identifiers

PMID28978912
PMCPMC5627285
OpenAlexW2759460654

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.