Evidence map›Paper›PMID 28978742›Full record

ArticleMolecular biology of the cell2017

Regulation of Arf activation occurs via distinct mechanisms at early and late Golgi compartments.

Margaret A Gustafson, J Christopher Fromme

Abstract read
In one paragraph

Article in Molecular biology of the cell, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 40 citations in OpenAlex.

  1. Knockout ofJournal of fungi (Basel, Switzerland) · 2026
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  7. Sec7 regulatory domains scaffold autoinhibited and active conformations.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
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  18. The Golgi Apparatus and its Next-Door Neighbors.Frontiers in cell and developmental biology · 2022
    Review
  19. Role of theFrontiers in cell and developmental biology · 2022
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Margaret A GustafsonDepartment of Molecular Biology and Genetics, Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY 14853.
J Christopher FrommeDepartment of Molecular Biology and Genetics, Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY 14853 jcf14@cornell.edu.
Cornell University · US

Funding

PREDOCTORAL TRAINING IN CELLULAR AND MOLECULAR BIOLOGYT32GM007273 · NIGMS · CORNELL UNIVERSITY ITHACA · PI BRETSCHER, ANTHONY P. · 1985 to 2019
$11.6M
Regulation of Arf GTPase activation at the trans-Golgi networkR01GM098621 · NIGMS · CORNELL UNIVERSITY · PI FROMME, J CHRISTOPHER · 2012 to 2020
$2.9M
NIGMS NIH HHS R01 GM098621NIGMS NIH HHS T32 GM007273
6 · The paper itself

Abstract

At the Golgi complex, the biosynthetic sorting center of the cell, the Arf GTPases are responsible for coordinating vesicle formation. The Arf-GEFs activate Arf GTPases and are therefore the key molecular decision-makers for trafficking from the Golgi. In

Indexed as

ADP-Ribosylation FactorsGolgi ApparatusGuanine Nucleotide Exchange FactorsMembrane ProteinsMonomeric GTP-Binding ProteinsProtein BindingProtein Transportrab GTP-Binding ProteinsSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsADP-Ribosylation FactorsGEA1 protein, S cerevisiaeGEA2 protein, S cerevisiaeGuanine Nucleotide Exchange FactorsMembrane ProteinsMonomeric GTP-Binding Proteinsrab GTP-Binding ProteinsSaccharomyces cerevisiae ProteinsYPT1 protein, S cerevisiae

Identifiers

PMID28978742
PMCPMC5706993
OpenAlexW2763177329

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.