Evidence map›Paper›PMID 28978739›Full record

ArticleMolecular biology of the cell2017

Geometric constraints alter cell arrangements within curved epithelial tissues.

Jean-Francois Rupprecht, Kok Haur Ong, Jianmin Yin, Anqi Huang, Huy-Hong-Quan Dinh, Anand P Singh, Shaobo Zhang, Weimiao Yu, Timothy E Saunders

Abstract read
In one paragraph

Article in Molecular biology of the cell, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 57 citations in OpenAlex.

  1. Article
  2. Article
  3. The role of geometry in morphogenesis.Development (Cambridge, England) · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Apico-basal intercalations enable the integrity of curved epithelia.Computational and structural biotechnology journal · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. The impact of cell size on morphogen gradient precision.Development (Cambridge, England) · 2023
    Article
  13. Review
  14. Article
  15. Thickness of epithelia on wavy substrates: measurements and continuous models.The European physical journal. E, Soft matter · 2022
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Jean-Francois RupprechtMechanobiology Institute, National University of Singapore, Singapore 117411.
Kok Haur OngIInstitute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*Star), Biopolis 138673, Singapore.
Jianmin YinMechanobiology Institute, National University of Singapore, Singapore 117411.
Anqi HuangMechanobiology Institute, National University of Singapore, Singapore 117411.
Huy-Hong-Quan DinhMechanobiology Institute, National University of Singapore, Singapore 117411.
Anand P SinghMechanobiology Institute, National University of Singapore, Singapore 117411.
Shaobo ZhangMechanobiology Institute, National University of Singapore, Singapore 117411.
Weimiao YuIInstitute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*Star), Biopolis 138673, Singapore dbsste@nus.edu.sg wmyu@imcb.a-star.edu.sg.
Timothy E SaundersMechanobiology Institute, National University of Singapore, Singapore 117411 dbsste@nus.edu.sg wmyu@imcb.a-star.edu.sg.
National University of Singapore · SGAgency for Science, Technology and Research · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Organ and tissue formation are complex three-dimensional processes involving cell division, growth, migration, and rearrangement, all of which occur within physically constrained regions. However, analyzing such processes in three dimensions in vivo is challenging. Here, we focus on the process of cellularization in the anterior pole of the early

Indexed as

Spatial AnalysisAnimalsCell Culture TechniquesCell DivisionCell MembraneCell MovementComputer SimulationDrosophila melanogasterDrosophila ProteinsEmbryonic DevelopmentEmbryo, NonmammalianEpithelial CellsEpitheliumModels, Spatial InteractionMorphogenesisOrganogenesisDrosophila Proteins

Identifiers

PMID28978739
PMCPMC5706987
OpenAlexW2762373197

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.