Evidence map›Paper›PMID 28978670›Full record

ArticleThe EMBO journal2017

Sterol transfer, PI4P consumption, and control of membrane lipid order by endogenous OSBP.

Bruno Mesmin, Joëlle Bigay, Joël Polidori, Denisa Jamecna, Sandra Lacas-Gervais, Bruno Antonny

Open access · bronzeAbstract read
In one paragraph

Article in The EMBO journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 122 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
122citing papers in PubMed, 1 pooled it
9.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

122 citing papers in PubMed, 1 synthesis or guideline pooled it, 239 citations in OpenAlex.

  1. Stay in touch with the endoplasmic reticulum.Science China. Life sciences · 2024
    Pooled it
  2. Article
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  4. Review
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  6. Article
  7. Subcellular Cartography of the Phosphoinositide Multiverse.Biochimica et biophysica acta. Molecular and cell biology of lipids · 2026
    Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. The Inner Nuclear Membrane Has a Unique Lipid Signature.BioEssays : news and reviews in molecular, cellular and developmental biology · 2025
    Review
  13. Article
  14. Article
  15. Review
  16. PI(4)P recruits CIDE proteins to promote the formation of unilocular lipid droplets during adipogenesis and hepatic steatosis.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  17. Article
  18. Article
  19. Article
  20. Article

62 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Bruno MesminUniversité Côte d'Azur, Inserm, CNRS, Institut de Pharmacologie Moléculaire et Cellulaire, Valbonne, France.ORCID 0000-0002-5437-3246
Joëlle BigayUniversité Côte d'Azur, Inserm, CNRS, Institut de Pharmacologie Moléculaire et Cellulaire, Valbonne, France.
Joël PolidoriUniversité Côte d'Azur, Inserm, CNRS, Institut de Pharmacologie Moléculaire et Cellulaire, Valbonne, France.
Denisa JamecnaUniversité Côte d'Azur, Inserm, CNRS, Institut de Pharmacologie Moléculaire et Cellulaire, Valbonne, France.
Sandra Lacas-GervaisUniversité Côte d'Azur, Centre Commun de Microscopie Appliquée, Nice, France.
Bruno AntonnyUniversité Côte d'Azur, Inserm, CNRS, Institut de Pharmacologie Moléculaire et Cellulaire, Valbonne, France antonny@ipmc.cnrs.fr.ORCID 0000-0002-9166-8668
Centre National de la Recherche Scientifique · FRUniversité Côte d'Azur · FR

Funding

European Research Council 268888
6 · The paper itself

Abstract

The network of proteins that orchestrate the distribution of cholesterol among cellular organelles is not fully characterized. We previously proposed that oxysterol-binding protein (OSBP) drives cholesterol/PI4P exchange at contact sites between the endoplasmic reticulum (ER) and the

Indexed as

Biological TransportCholestenonesCholesterolDicarbethoxydihydrocollidineEndoplasmic ReticulumEpithelial CellsFluorescent DyesGene ExpressionHeLa CellsHumansLipid DropletsMinor Histocompatibility AntigensOxysterol Binding ProteinsPhosphatidylinositol PhosphatesPhosphotransferases (Alcohol Group Acceptor)Receptors, SteroidCholestenonesCholesterolDicarbethoxydihydrocollidinedihydroethidineFluorescent DyesMinor Histocompatibility AntigensOSW 1Oxysterol Binding Proteinsphosphatidylinositol 4-phosphatephosphatidylinositol phosphate 4-kinasePhosphatidylinositol PhosphatesPhosphotransferases (Alcohol Group Acceptor)PI4KB protein, humanReceptors, SteroidSaponinscholesterolGolgi apparatuslipid‐transfer proteinmembrane contact sitephosphatidylinositol 4‐phosphate

Identifiers

PMID28978670
PMCPMC5666618
OpenAlexW2761934676

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.